Despite the widespread recognition that mucosal irritation is a cardinal feature of "sick-building syndrome," few data exist on the cause, natural history, or pathophysiology of upper respiratory mucous membrane irritation. The baseline prevalence of nasal symptoms among building occupants is often 20%, but in some studies it is as high as 50 to 60%. New techniques of nasal challenge and analys...

Hereditary angioedema is a rare (1:50,000) hereditary chronic disease from the group of primary immunodeficiencies, which manifests in form recurrent skin and mucous membrane edema respiratory tract gastrointestinal tract. Pathogenesis this are associated with an increased risk number cardiovascular pathologies, complexity management choosing optimal treatment methods. This case report demonstr...

Rhinosporidiosis is a chronic, granulomatous, muco-cutaneous infection caused by Rhinosporidium seeberi . The non-contagious and sporadic in humans, affecting predominantly the mucous membrane of upper respiratory tract. It quite an uncommon condition seldom affects oral mucosa. clinical presentation this cavity can mimic many other conditions. Here, we report unique case recurrent rhinosporidi...

BACKGROUND Clinical data on the association of diabetes mellitus with common infections are virtually lacking, not conclusive, and often biased. We intended to determine the relative risks of common infections in patients with type 1 and type 2 diabetes mellitus (DM1 and DM2, respectively). METHODS In a 12-month prospective cohort study conducted as part of the Second Dutch National Survey of...

Scleroma is an endemic disease, spread mainly in Western Ukraine, Belarus and adjacent areas. refers to chronic diseases that aff ect the mucous membrane of upper respiratory tract. This clinical case attracted attention due rare diagnosis patient’s age (88 years), most di ffi cult localization process terms course, pronounced concentric funnel- shaped narrowing trachea 5-6 mm lumen for 4-5 cm lon...