نتایج جستجو برای: mtuberculosis

تعداد نتایج: 1  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2017
Stefan Köster Sandeep Upadhyay Pallavi Chandra Kadamba Papavinasasundaram Guozhe Yang Amir Hassan Steven J Grigsby Ekansh Mittal Heidi S Park Victoria Jones Fong-Fu Hsu Mary Jackson Christopher M Sassetti Jennifer A Philips

Mycobacterium tuberculosis' success as a pathogen comes from its ability to evade degradation by macrophages. Normally macrophages clear microorganisms that activate pathogen-recognition receptors (PRRs) through a lysosomal-trafficking pathway called "LC3-associated phagocytosis" (LAP). Although Mtuberculosis activates numerous PRRs, for reasons that are poorly understood LAP does not substanti...

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