background and purpose: multiple sclerosis (ms) is a chronic disease that gives rise to a number of unpleasant symptoms that can be difficult to manage by conventional means. there are some aspects of ms-related disability which can be improved by using deep brain stimulation (dbs); particularly movement disorders, such as tremor. the research aim is to study the effect of dbs on ms tremor with...

Background: Multiple Sclerosis (MS) is a demyelinating disorder of the central nervous system. Tremors are a common problem in the patients suffering from MS which is mostly observed in the arms but can also affect the other body parts. There have been few studies on tremors among the MS patients.  Objectives: This study is the first to report the prevalence of tremor in a group of MS pat...

BACKGROUND Given that tremor is one of the most prevalent and disabling features of multiple sclerosis (MS), we will review the most significant milestones in tremor in this disease in recent years, focusing on prevalence, clinical features, anatomical basis, and treatment. METHODS Data for this review were identified by searching MEDLINE with the search terms "multiple sclerosis" and "tremor...

Background: Given that tremor is one of the most prevalent and disabling features of multiple sclerosis (MS), we will review the most significant milestones in tremor in this disease in recent years, focusing on prevalence, clinical features, anatomical basis, and treatment. Methods: Data for this review were identified by searching MEDLINE with the search terms ‘‘multiple sclerosis’’ and ‘‘tre...

Patients with intention tremor due to multiple sclerosis (MS) exhibit an increased reliance on visual feedback in the sensorimotor control of slow goal-directed movements. In the present study, the use of proprioceptive information was investigated in MS patients with intention tremor compared to MS patients without tremor and healthy controls. Tendon vibration was applied to the wrist extensor...

Intention tremor is related to lesions in the cerebellum or connected pathways. Intention tremor amplitude decreased after peripheral arm cooling in patients with multiple sclerosis (MS), likely caused by a reduction of muscle spindle afferent inflow, while amplitude increased when muscle spindles were artificially stimulated by tendon vibration. This study investigated the contribution of peri...

OBJECTIVES (1)To describe the prevalence and severity of tremor in patients with multiple sclerosis (MS) registered within a large North American MS registry; (2) to provide detailed descriptions on the characteristics and severity of tremor in a subset of registrants and (3) to compare several measures of tremor severity for strength of agreement. SETTING The North American Research Committe...

OBJECTIVES To compare action tremor (AT) during manual tracking in normal subjects and patients with multiple sclerosis with tremor (MS-tremor group) and without tremor (MS-no tremor group), and to differentiate tremor occurring predominantly around the distal joint from that involving the proximal joints of the arm. METHODS Subjects performed both a visually guided ramp tracking task using w...

The influence of oscillatory activity in the motor system on the generation of voluntary movement has been previously studied by revealing temporal coupling between voluntary movements and associated physiological or pathological tremor. The present study aims to investigate whether there is any temporal correlation between the onset of a rapid reactive movement and the action tremor at the wri...

To identify those multiple sclerosis (MS) patients with disabling tremor who will benefit most from thalamotomy, measurements of frequency spectra of involuntary movements during visually guided wrist tracking were carried out in 11 consecutive patients with MS before and after ventrolateral thalamotomy. Thalamotomy was significantly more effective if patients had disruptive action tremor which...