To the Editor: Multiple primary lung cancer (MPLC) refers to the synchronous or metachronous appearance of more than one primary lung cancer in a single patient. The diagnosis of MPLC is complicated and it is often difficult to differentiate MPLC from metastatic lung cancers based on radiologic and histopathologic criteria alone. Moreover, the therapeutic regimens and prognosis for early MPLC a...

Multiple primary lung cancer (MPLC) is an uncommon entity of the primary lung cancer. With the widespread use of early detection tools such as multislice spiral computed tomography (CT), positron emission tomography (PET), and the better survival results after resection of primary lung cancer, more and more MPLC have been detected. However, the current diagnostic and therapeutic methods cannot ...

The incidence of synchronous multiple primary lung cancer (MPLC) is increasing. However, present diagnostic methods are unable to satisfy the individualized treatment requirements of patients with MPLC. The present study aimed to establish a quantitative mathematical model and analyze its diagnostic value for distinguishing between MPLC and cases of the histologically similar disease, intrapulm...

BACKGROUND AND PURPOSE Multiple primary lung cancers (MPLC) are not an uncommon presentation. Current guidelines recommend a curative approach when early-stage MPLC is diagnosed as favorable outcomes have been reported after surgery. We studied outcomes following stereotactic ablative radiotherapy (SABR). MATERIALS AND METHODS Following review of imaging and pathology at a multi-disciplinary ...

Objective: The development of a multiple primary lung cancer (MPLC) is not rare in long-term survivors after curative resections. We analysed our experience in order to verify surgical results and long-term survival in our patients. Methods: From 1971 to 1999, 80 patients with MPLC (two tumours each, total 160) were treated at the Division of Thoracic Surgery of the University of Padua. Our cri...

A single multi-plane light convertor (MPLC) is applied to simultaneously mitigate turbulence-induced crosstalk and demultiplex two orbital angular momentum (OAM) multiplexed channels for a free-space optical link. Comprised of six programmable phase planes, the MPLC placed at receiver side turbulence mitigation channel demultiplexing. Propagating through cascaded coaxial turbulence-distorted OA...

We present a case of multiple primary lung cancer(MPLC) displaying heterogeneous EGFR and PTEN molecular profiles. Considering the physical condition of patients, the patient underwent surgical resection of the right lung lesion displaying gefitinib-insensitive and continued gefitinib treatment for the gefitinib-sensitive lesions in the left lung. As far as we know, this is the first report doc...

Due to recent advances in high-resolution detection technology, multiple primary lung cancer (MPLC) is becoming an increasingly common diagnosis. However, the genotype-phenotype correlations in MPLC patients have not yet been assessed. In this study, we analyzed the clinical and pathological data for 129 consecutive MPLC patients who received curative surgery at the Tongji University Shanghai P...

High-dimensional entanglement offers a variety of advantages for both fundamental and applied applications in quantum information science. A central building block such is programmable processor entangled states, which crucial the certification, manipulation, distribution high-dimensional entanglement. The leading technology processing photons integrated multiport interferometers. However, devi...

We evaluated the performance characteristics of three real-time reverse transcription-PCR test systems for detection and quantification of hepatitis C virus (HCV) and performed a direct comparison of the systems on the same clinical specimens. Commercial HCV panels (genotype 1b) were used to evaluate linear range, sensitivity, and precision. The Roche COBAS TaqMan HCV test for research use only...