Despite a lot of research, the etiology and progression of breast cancer remain incompletely understood. Recently, human cytomegalovirus (HCMV) was reported as a risk factor for breast cancer. The aim of this study was to know whether breast cancer could be caused by cytomegalovirus or not? In this experiment seventeen samples of RAZI/A mice with spontaneous breast cancer were being gathered fr...

despite a lot of research, the etiology and progression of breast cancer remain incompletely understood. recently, human cytomegalovirus (hcmv) was reported as a risk factor for breast cancer. the aim of this study was to know whether breast cancer could be caused by cytomegalovirus or not? in this experiment seventeen samples of razi/a mice with spontaneous breast cancer were being gathered fr...

Strong species specificity and similar tropisms suggest mouse cytomegalovirus (mCMV) as a potential vector for transgenes into human cells. We reexamined the dogma that mouse cytomegalovirus cannot productively replicate in human cells and found that mouse cytomegalovirus can produce infectious particles albeit at a level that does not sustain an infection. This finding demonstrates that mouse ...

Some years ago, we found that Axial organ (AO) cells exerted an induced and spontaneous cytotoxicity against SP2 MBL2 mouse tumoral cells. Recently, discovered a sea star Igkappa gene with immune properties. This was first, inserted in CMV (cytomegalovirus) finally plasmid called « young » plasmid. In the present experiment IGKappa cloned HeK human to produce specific protein. The induced« prot...

Cytomegalovirus (CMV) induced autophagy affects virus replication and survival of the infected cells. The purpose this study was to investigate role inhibition by 3-methyladenine (3-MA) on murine cytomegalovirus (MCMV) whether it is associated with caspase-3 dependent apoptosis. eyecup isolated from adult C57BL/6J mice (6–8 weeks old) mouse embryo fibroblast cells (MEFs) were MCMV K181 strain, ...