iran is an important endemic focus area of cystic hydatid disease where several intermediate host species are commonly infected with echinococcus granulosus . annually, most livers are shipped out, stored away, or destroyed due to contamination among livestock. for instance, in aleshtar (lorestan province), liver and lung losses due to hydatid cysts during 2002-2003 were approximately 864,360,0...

background : the high incidence of breast cancer in young women in iran and its resultant problems for families show the necessity of exploring studies conducted in this field. the present research was conducted to determine the volume of scientific production on breast cancer in iran, and to compare it with that of other countries in the middle east. methods : this systematic review study used...

the prevalence of obesity as one of the most health concerns has increased globally. this kind of disease has been accounted for several diseases such as type 2 diabetes, different types of cancer, heart disease, and alzheimer. obesity is a multifactorial disease that both environmental factors and genetics play important role in its susceptibly. in molecular biology, characterization of the ad...

the interactions between platinum complexes and human serum albumin (hsa) play crucial roles in the distribution, metabolism, and activity of platinum-based anticancer drugs. octahedral platinum (iv) complexes represent a significant class of anticancer agents that display molecular pharmacological properties different from cisplatin. in this study, the interaction between two pt(iv) complexes ...

A set of Xanthohumol derivatives were selected and molecular docking studies of these ‎compounds on thioredoxin reductase were conducted. Based on new structural patterns using in ‎silico-screening study, new potent lead compounds were designed. The results due to validated ‎docking protocols lead to find that Thr58, Gly57, Gly21, Asp334, Glu163, Ala130, IIe332, ‎Val44 and Gly132 are the main a...

The cytosol is the major environment in all bacterial cells. The true physical and dynamical nature of the cytosol solution is not fully understood and here a modeling approach is applied. Using recent and detailed data on metabolite concentrations, we have created a molecular mechanical model of the prokaryotic cytosol environment of Escherichia coli, containing proteins, metabolites and monat...