نتایج جستجو برای: molconn

تعداد نتایج: 4  

Journal: :international journal of environmental research 2011
d.x. jiang y. li j. li g.x. wang

the purpose of this work is to develop robust and interpretable quantitative structure”activity relationship (qsar) models for assessing the aquatic toxicity of phenols using a combined set of descriptors encompassing the logp and recently developed variables (monconn-z variables). the used dataset consists of 250 chemicals with toxicity data to the ciliate tetrahymena pyriformis. for each com...

Journal: :international journal of environmental research 0
d.x. jiang northwest a&f university, xinong road 22th, yangling, 712100, china g.x. wang northwest a&f university, xinong road 22th, yangling, 712100, china g.x. wang northwest a&f university, xinong road 22th, yangling, 712100, china g.x. wang northwest a&f university, xinong road 22th, yangling, 712100, china

the purpose of this work is to develop robust and interpretable quantitative structure”activity relationship (qsar) models for assessing the aquatic toxicity of phenols using a combined set of descriptors encompassing the logp and recently developed variables (monconn-z variables). the used dataset consists of 250 chemicals with toxicity data to the ciliate tetrahymena pyriformis. for each comp...

Journal: :Journal of chemical information and computer sciences 2004
Richard D. Beger John F. Young Hong Fang

The ability to predict organ-specific carcinogenicity would aid FDA reviewers in evaluating new chemical applications. A NCTR liver cancer database (NCTRlcdb) containing 999 compounds has been developed with three sets of descriptors. The NCTRlcdb has Cerius2, Molconn-Z, and (13)C NMR descriptors for each compound. Each compound in the database was assigned a liver cancer or a nonliver cancer c...

Journal: :Journal of chemical information and modeling 2008
Huixiao Hong Qian Xie Weigong Ge Feng Qian Hong Fang Leming Shi Zhenqiang Su Roger Perkins Weida Tong

Research applications in chemoinformatics and toxicoinformatics increasingly use representations of molecules in the form of numerical descriptors that capture the structural characteristics and properties of molecules. These representations are useful for ADME/toxicity prediction, diversity analysis, library design, QSAR/QSPR, virtual screening, and other purposes. Molecular descriptors have r...

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