A simple spectrophotometric method for the determination of tranexamic acid in pure form and pharmaceutical preparations was developed. The method is based on coupling tranexamic acid with 2,6-dichloroquinone-4-chlorimide (DCQ) in dimethyl sulfoxide (DMSO) to produce a colored product which absorbs maximally at wavelength ( ) 670nm. The molar ratio of tranexamic acid: DCQ is 2:1. Beer’s law is ...

A simple, sensitive, rapid and accurate spectrophotometric method was developed for the determination of risedronate, a bisphosphonate drug important for the treatment of a variety of bone diseases, in raw material and pharmaceutical formulations. The proposed method is based on complex formation between risedronate and Cu (II) ions in acetate buffer of pH5.5. The optimum conditions for this re...

a simple, acurate and rapid spectrophotometric method for determination of sulphite thiamine hydrochloride (B1) is described. This used proton transfer reaction between ion with xylenol orange at pH(7.6) to develop red colour adduct that maximum absorption 580 nm. was by bleaching the product (xylenol orange-sulphite) optimum conditions established sulphite. Beer’s law obeyed in concentration r...

A novel approach is reported for the development of fluorogenic esterase reporters using alpha-cyano-containing esters as substrates. After ester hydrolysis, the released alcohol, a cyanohydrin, rapidly eliminates HCN to yield the corresponding aldehyde resulting in strong fluorescence. The pi conjugation of the resulting aldehyde also greatly enhances UV absorption and red shifts fluorescence ...

Two simple, sensitive, accurate and economic methods A and B have been developed for the quantitative estimation of vancomycin hydrochlorid (VHC) and its formulations using another two drug compounds as a coupling reagents.The proposed methods are based on a coupling reaction between VHC and diazotized procain (method A) or diazotized sulphacetamide sodium (method B) in alkaline medium to form ...

We demonstrate a multiband plasmonic absorber based on transverse phase resonances. We show that the modification of conventional metallic surfaces of T-shape grooves can cause mode splitting of the plasmonic waveguide cavity modes due to lattice scattering and all the new resonant modes exhibit large absorbtivity greater than 90%. Some of the generated absorption peaks have wide-angle characte...

Since the inception of the present project in May of 1998 the Clemson, Furman, and Ga. Tech. laboratories are continuing the synthesis and characterization of unique monomeric and oligomeric molecules. These moieties when polymerized into or onto fibers and films will change the color of the substrate material upon application of an electric field. This process will enable the development of “t...

introdouction: impacted mandibular third molar surgery may affect periodontal status of the adjacent second molar. the purpose of this study was to evaluate the changes in periodontal health parameters distal to the adjacent second molar following surgical extraction of an impacted mandibular third molar. materials and methods: we selected 50 subjects with a mean age of 22.8 (ranging from 18 to...

objective: the present study assessed the association of size, axial angulation, developmental stage and bud position of the mandibular third molar with the second molar impaction in patients with mandibular second molar impaction. methods: in this descriptive-analytical study (case-control design), dental records of 5,420 patients in the age range of 12-15 years who underwent orthodontic treat...