oil in water emulsions have attracted considerable attention in food industry due to their large applications. in this study, the effect of thermal treatment on oil in water emulsions (o/w) containing 40% oil was studied. the emulsions were prepared using xanthan gum, guar gum and carboxymethyl cellulose as stabilizer and polyoxyethylen sorbitan monooleat as emulsifier. a mixture design was use...

the objective of the current study was to develop and optimize a sublingual tablet formulation of captopril which is an effective drug in the treatment of hypertension. captopril containing tablets were prepared by direct compression method using different ingredients such as polyvinyl pyrrolidone, starch 1500, sodium starch glycolate and lactose (independent variables) and magnesium stearate, ...

Many practical experiments on mixtures (where the components sum to one) include additional lower or upper bounds on components, or on linear combinations of them. Usually theory cannot be used to obtain a good design, and algorithmic methods are necessary. Some of the available methods are discussed. Their performance is evaluated on some examples, and the form of the optimal design is investi...

Mixture design has been used to identify possible interactions between mutagens in a mixture. In this paper the use of mixture design in multidimensional isobolographic studies is introduced. Mutagenicity of individual nitro-polycyclic aromatic hydrocarbons (PAH) was evaluated is an organic extract of diesel exhaust particles (DEPs). The particles were extracted with dichloromethane (DCM). Afte...

rutting of hot mix asphalt pavements due to increased number of heavy vehicles, especially in tropical regions, causes several performance problems. large stone asphalt mixtures have more stiffness and shear resistance and so more rutting resistance compared to conventional mixtures. hence, using these mixtures in thick layers of hot mix asphalt pavements at tropical regions could be an appropr...

In this research, the selective flotation of galena and sphalerite minerals was evaluated from a pyrite-rich lead-zinc sample. An optimum mixture of selective collectors against pyrite and also organic/inorganic pyrite depressants was obtained in the flotation of galena and sphalerite by an experimental mixture design. The effect of different collectors and pH values were investigated in the ob...

A simplex-centroid design for q mixture components comprises of all possible subsets of the q components, present in equal proportions. The design does not contain full mixture blends except the overall centroid. In real-life situations, all mixture blends comprise of at least a minimum proportion of each component. Here, we introduce simplex-centroid designs which contain complete blend...