rye (secale cereale) chromosome 1rs harbors multiple genes including lr26, sr31, yr9 and pm8 conferring disease resistance and tolerance to abiotic stresses. the introgression of the rye 1r chromosome short arm has enormously contributed to increase of genetic diversity in wheat. utilization of such translocations in breeding programs demands identification of wheat germplasm possessing the whe...

In this study, we investigated the chromosome numbers of some endemic species distributed in East and South-East Iran. The mitotic chromosome counts were presented for the first time for six species in three angiosperm families including: Linaria iranica (2n=12), Nanorrhinum campyloceras (2n=18), Chaenorhinum grossecostatum (2n=24) (Plantaginaceae), Gaillonia bruguieri (Rubiaceae) (2n=22), Nepe...

BACKGROUND Counting mitoses is subjective and time-consuming. The adjunctive diagnostic utility of a recently reported mitotic marker, phosphohistone H3 (PHH3), was investigated in gastrointestinal stromal tumors (GISTs). METHODS We reviewed 77 GISTs for several proliferative indices. These included the mitotic count per 50 high power fields (HPFs), the immunohistochemical Ki- 67 labeling ind...

Original meiotic or mitotic chromosome counts are presented for 17 species in 12 families of angiosperms from Iran. Chromosome counts for Amberboa nana, n=16 (Asteraceae) and Camelina rumelica subsp. transcapica, n=13 (Brassicaceae) are repoted for the first time. Chromosome numbers for six species including: Rhagadiolus stellatus (n=5), Campanula raponcoloides (n=34), Campanula trachelium (n=1...

BACKGROUND Quantitative methods in combination with other objective prognostic criteria can improve the evaluation of a cancer patient's prognosis, and possibly predict response to therapy. One of the important prognostic and predictive markers is the mitotic count, which has proven valuable in many aspects. In this study, the prognostic value of the mitotic count was assessed in breast cancer ...

Leiomyomas occur at various anatomical sites. While gastrointestinal leiomyomas are relatively uncommon, the female genital tract leiomyomas are one of the most common benign tumors. It is important to rule out the possibility of leiomyosarcoma whenever examining leiomyomas. At times this may be quite taxing as the nuclear atypia may be minimal. Not only many sections have to be submitted but a...

AIMS To determine the prognostic usefulness of the Nottingham histological grade (NHG) and its components in a series of 270 patients with stage pT1N0M0 breast cancer with a median follow up of 12.5 years. METHODS Microscopic slides were re-examined and the degree of tubule formation, nuclear pleomorphism, and mitotic counts were assessed and scored according to the suggested guidelines. The ...

Evaluation of cell proliferation has been long recognized in pathology as a mainstay of diagnosis and important in the prognostication of a variety of neoplasms. Routine light microscopic evaluation of mitotic activity has long served as a reasonable assessment of cell proliferation. Counting mitotic figures has the advantage of being inexpensive and relatively quick. The main objections levele...

SUMMARY Effects on mitosis in mouse vaginal and rectal epithelium were used to screen antimitotic properties of drugs given i.p. Test drugs were given i.p. at time zero, podophyllin was injected at 2 hr, and the animals were killed at 8 hr. Both vagina and rectum were removed en bloc. Mitotic cells in the epithelia were counted histologically. The validity of the system was ascertained by testi...