نتایج جستجو برای: mitogen
تعداد نتایج: 27707 فیلتر نتایج به سال:
Background & Objective : We study Surrogacy validation of Th1 and Th2, when the true endpoint is Long-term Skin Effects of Exposure to Mustard Gas based on “Martyrs and Veterans Affair” assignment. Materials & Methods : This study is a part of Sardasht-Iran cohort study. 327 chemical victims of sulfur mustard from Sardasht and 128 controlled, totally 500 persons, are studied. Results : Tr...
background and objectives: mycoplasma arthritidis mitogen (mam) superantigen has been shown to induce chronic arthritis, which resembles human rheumatoid arthritis (ra) in a rodent model. however, its role as a causative agent in human ra is not well understood yet. the aim of this study was to investigate the presence of mam superantigen gene in the synovial fluid (sf) of ra patients. material...
Background and Objective: Here,it is tried to assess an insight behind using IFN-G,IL-2,IL-4,and IL-10 biomarkers as potential surrogate endpoints for skin diseases caused by exposure to mustard gas. Potentially,a biomarker is a valid surrogate if assessment of the treatment effect based on surrogate endpoint leads to the same result based on true clinical endpoint. Materials and Methods: In S...
diabetic retinopathy is the lead among causes of blindness in north america. glucose-induced endothelial injury is the most important cause of diabetic retinopathy and other vascular complications. extracellular signal-regulated kinase 5 (erk5), also known as big mitogen-activated protein kinase 1 (bmk1), is a member of mitogen-activated protein kinases (mapk) family. physiologically, it is cri...
oxymatrine, a potent monosomic alkaloid extracted from chinese herb sophora japonica (sophora flavescens ait.). possesses anti-inflammatory activittyes. this study was designed to investigate the effects of oxymatrine on nuclear factor–kappa b (nf-κb) and mitogen-activated protein kinase (mapk)-dependent inflammatory responses in lipopolysaccharide (lps)-activated microglia. in this paper, bv2...
Introduction Trauma patients are susceptible to coagulopathy and dysfunctional immune responses. Mesenchymal stromal cells (MSCs) at the forefront of cellular therapy revolution with profound immunomodulatory, regenerative, therapeutic potential. Routine assays assess immunomodulation activity examine MSC effects on proliferation peripheral blood mononuclear (PBMCs) take 3–7 days. Assays that c...
introduction: increased oxidative stress is widely accepted to be a factor in the development and progression of alzheimer’s disease. triazine derivatives possess a wide range of pharmacological activities including anti-oxidative and anti-in.ammatory actions. in this study, we aimed to investigate the possible protective effect of 3-thioethyl-5,6-dimethoxyphenyl-1,2,4-triazine (tedmt) on h2o2-...
beauveria spp. as entomopathogenic fungi have extremely diverse insect host ranges.here, a comparative transcript analysis of a bassiasin i (bsni), a dipeptidyl peptidase (dpp), a cytochrom p450 monooxygenase (cyp52), a mitogen activated protein kinase (mapk), and a neuronal calcium sensor 1 (ncs) in two isolates of beauveria bassiana., with low and high virulence, were carried out. for this, i...
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