Background: Lichen planus is a common dermatological condition. Many treatment options have been discussed in literature, each with its own risk profile. Betamethasone pulse therapy is one of the effective therapies mentioned.The objective of this study was to find out whether oral betamethasone mini pulse therapy is effective in lichen planus.Methods: A total of 40 pat...

Background: Pulse therapy is a type of systemic management in which large amounts of medications are administered to patients in short time and intervals (e.g. weekly) to get the stronger effects of medication sooner and avoid long term use of them. Objective: To determine how therapy-resistant dermatology diseases respond to oral minipulse steroids . Methods: Articles with Mesh terms "pulse th...

A 22-year-old man presented with alopecia areata on the scalp of six months’ duration. It was progressive both in terms of size and number of lesions. He gave no history of atopy, hypertension or diabetes. He had been intermittently applying various topical corticosteroids and salicylic acid and had been injected intralesional triamcinolone twice, but without any improvement. His routine hemato...

background: to manage relapsing‑remitting multiple sclerosis (ms) in the course of acute exacerbations, methylprednisolone (mp) (medrol or solu‑medrol), has the ability to lock the injured blood‑brain barrier and decrease irritation in the central nervous system. the aim of this preliminary study was to investigate the frequency and time interval related to mp pulse therapy in patients with ms....

Pubertal development in female rats is characterized by increased LH levels and the appearance of estrogen-dependent afternoon LH mini-surges. In these studies we performed the first analysis of GnRH patterns in peripubertal rats to determine whether there are similar changes in pulsatile GnRH release. Microdialysis samples were collected at 5-min intervals throughout a 5-h afternoon period fro...

introduction application of near-infrared absorbing nanostructures can induce hyperthermia, in addition to providing more efficient  photothermal effects. gold-gold sulfide (ggs) is considered as one of these nanostructures. this study was performed on a tissue-equivalent optical-thermal phantom to determine the temperature profile in the presence and absence of ggs and millisecond pulses of a ...