this paper discusses the simulation study carried out for proposing one-piece lean line layout with features of lean manufacturing. the lean initiatives that can be addressed are, introducing kanban replenishment sys-tem, better work-in-process, changing the layout, visual management techniques, standardized work for the re-duction of cycle time, number of workers, number of setups. to improve ...

To provide efficient and flexible material transport, inplant milk-run systems are used by many companies. However, the large number of influencing factors makes in-plant milk-run systems complex, while dependencies and blockages, e.g. overtaking or stopping, require a dynamic approach to examination. Thus we developed a generic simulation model focusing on traffic situations in in-plant road s...

The objective of vehicle routing problem is usually to minimize the total traveling distance or cost. But in practice, there are a lot of problems needed to minimize the fastest completion time. The milk-run vehicle routing problem (MRVRP) is widely used in milk-run distribution. The mutation ACO is given to solve MRVRP with fastest completion time in this paper. The milk-run VRP with fastest c...

This study determined the effect of nutritional supplementation throughout endurance exercise on whole-body leucine kinetics (leucine rate of appearance [Ra], oxidation [Ox], and nonoxidative leucine disposal [NOLD]) during recovery. Five trained men underwent a 2-h run at 65% VO(2max), during which a carbohydrate (CHO), mixed protein-carbohydrate (milk), or placebo (PLA) drink was consumed. Le...