background: preeclampsia is a pregnancy complication with unknown etiology and its incidence is associated with genetic and environmental factors. there are inconsistent reports related to the role of endothelial nitric oxide synthase (enos) 4a/b polymorphism on the risk of preeclampsia development. the aim of the present study was to investigate the possible influence of enos 4a/b and its syne...

Background and Objective: The aim of this study was to determine the level of plasma high sensitive c-reactive protein (hs-CRP) in preeclampsia and to compare hs-CRP levels between normal pregnant women, mild preeclamptic, and severe preeclamptic women. Materials and Methods: Serum hs-CRP levels were inv...

Endothelial dysfunction is thought to be a central pathogenic feature in preeclampsia on the basis of elevated adhesion molecules. The aim of the present study was to compare the levels of soluble vascular cell adhesion molecule-1 (sVCAM-1), intercellular adhesion molecule-1 (sICAM-1) and E-selectin (sE-selectin) in sera of normal and preeclamptic pregnancies. We studied the serum levels of sVC...

INTRODUCTION This study was carried out to investigate changes in the plasma leptin concentrations during preeclampsia treatment and to determine whether antihypertensive treatments, aimed at decreasing leptin levels, would improve foetal outcomes. METHODS A prospective study was undertaken in 57 pregnant women with preeclampsia (37 with mild and 20 with severe preeclampsia) and 46 normal pre...

Background Vitamin D deficiency is associated with physiologic changes that are similar to pathogenesis of preeclampsia. Although association of vitamin D and preeclampsia has been studied previously, their results are not consistent. The aim of this study was to investigate the relationship of serum vitamin D and calcium with preeclampsia severity. Materials and Methods: This case- control st...

OBJECTIVE To determine whether early administration of aspirin prevents severe and mild preeclampsia. STUDY DESIGN A systematic review and meta-analysis of randomized controlled trials were performed. Studies in which women were randomized at or before 16 weeks' gestation to low-dose aspirin versus placebo or no treatment were included. The outcomes of interest were severe preeclampsia and mi...

background and objective: the aim of this study was to determine the level of plasma high sensitive c-reactive protein (hs-crp) in preeclampsia and to compare hs-crp levels between normal pregnant women, mild preeclamptic, and severe preeclamptic women. materials and methods: serum hs-crp levels were investigated in 40 cases of normal pregnant women, 37 cases with mild preeclampsia and 38 cases...

Background. Epicardial fat tissue, another form of visceral adiposity, has been proposed as a new cardiometabolic risk factor, and the possible association of epicardial fat with hypertension has been shown in some recent studies. Although epicardial fat thickness (EFT) is associated with hypertension, the relationship between preeclampsia and EFT is still unknown. The purpose of this paper is ...