objective this study was conducted to evaluate the preventive effect of lamotringine on migraine aura and migraine attacks in children, afflicted with classic migraine. material & methods conducted between october 2005 and april 2008 in the neurology clinic of kashani hospital,  shahrekord, this study was a clinical trial, aimed at evaluating the prophylactic effects of lamotringine administere...

abstract background: dysfunction of the autonomic nervous system has long been a subject of considerable debate and a large number of studies have disclosed contradictory results. the aim of this study was to compare cerebral vasomotor reactivity in migraine with aura (mwa) patients with migraine without aura (mwo) ones. methods: ten mwa patients (7 females and 3 males mean age: 39.70 years, sd...

conclusions headaches, particularly migraine without aura, are a common occurrence in pregnancy in our population. migraine severity is positively associated with high blood glucose levels. results the headache prevalence during pregnancy was 69% in the women with diabetes and 64% in the women without diabetes. a positive unilateral distribution was observed in 51% of the cases and 36.3% of the...

INTRODUCTION Persistent migraine aura without headache is an extremely rare condition. The International Headache Society defines various subtypes of migraines, including "persistent migraine aura without infarction" and "typical aura without headache." CASE PRESENTATION We describe the case of a 21-year-old Asian woman with a history of migraine without aura who had (as her first aura episod...

Migraine with aura is prevalent in high-altitude populations suggesting an association between migraine aura and hypoxia. We investigated whether experimental hypoxia triggers migraine and aura attacks in patients suffering from migraine with aura. We also investigated the metabolic and vascular response to hypoxia. In a randomized double-blind crossover study design, 15 migraine with aura pati...

BACKGROUND AND PURPOSE Five single-nucleotide polymorphisms (SNPs) (rs4379368, rs10504861, rs10915437, rs12134493 and rs13208321) were recently identified in a Western population with migraine. These migraine-associated SNPs have not been evaluated in a Han Chinese population. This study investigated the associations of specific SNPs with migraine in a Han population. METHODS This was a case-...

OBJECTIVE To determine whether acute migraine treatment outcome is different in migraine with aura compared with migraine without aura. METHODS We examined pooled outcome data for sumatriptan treatment of migraine with and without aura from the sumatriptan/naratriptan aggregate patient database. We also examined similar outcome data for inhaled dihydroergotamine (DHE) from a single, large ran...

OBJECTIVE We evaluated the current evidence on the association between migraine, including aura status, and cervical artery dissection. METHODS We performed a systematic review and meta-analysis of studies investigating the association between migraine or migraine subtypes (e.g. migraine with aura) and cervical artery dissection published through October 2010. RESULTS We identified five cas...

there are several conflicting reports about the eeg of the migraineurs. in this study we report the ictal and interictal eegs of 100 migraineurs, in comparison with control group. the range age for patient and control groups were 9-48 (mean: 26 ± 1.8) and 10-46 (mean: 23 ± 2.1) years respectively. 32% of the patients were less than 14 years old and the remaining 68% were more than 14 years. in ...

Persistent aura without infarction, a rare migraine disorder, is defined by aura symptoms that persist for >1 week without radiological evidence of cerebral infarction. To unveil its pathophysiological mechanisms, this study used magnetoencephalography to characterize the visual cortex excitability in persistent aura by comparison with episodic and chronic migraine. We recruited six patients wi...