background: differentiation between the muscularis mucosae (mm) and muscularispropria (mp) of the bladder remains challenging. objective: to identify mm- and mp-specific antigens that could be of potential value for staging of urothelialcarcinomain a pilot study. method: the expression of 12 protein antigens in 11 human bladder specimens was examined. there were 5 post radical cystectomy specim...

We show that the static friction force which must be overcome to render a sticking contact sliding is reduced if an external torque is also exerted. As a test system we study a planar disk lying on a horizontal flat surface. We perform experiments and compare with analytical results to find that the coupling between static friction force and torque is nontrivial: It is not determined by the Cou...

background: plasmodium vivax is the most widespread species of plasmodium in humans and causing about 80 million clinical cases annually. this study was under-taken to detect p. vivax in asymptomatic treated vivax malaria patients to trace la-tent/sub-patent malaria infection. method: the venous blood of all detected cases with p. vivax in bashagard, minab and roodan districts in hormozgan prov...

Background: Differentiation between the muscularis mucosae (MM) and muscularispropria (MP) of the bladder remains challenging. Objective: To identify MM- and MP-specific antigens that could be of potential value for staging of urothelialcarcinomain a pilot study. Method: The expression of 12 protein antigens in 11 human bladder specimens was examined. There were 5 post radical cystectomy specim...

The aim of the presented system is simplification and speedup of the daily pathological examination routine. The system combines telepathology with computer-aided diagnostics algorithms. To the best of our knowledge, this is the first approach proposing such a comprehensive method. Our system is designed to accumulate knowledge through a learning process during diagnostics. Our system targets i...

Molecular electronics and nanoscale chemical sensors could allow the construction microscopic sensors capable of detecting patterns of chemicals in a fluid. Information from a large number of such devices flowing passively in the bloodstream allows estimates of the properties of tiny chemical sources in a macroscopic tissue volume. We use estimates of plausible device capabilities to evaluate t...

Introduction and purpose Microscopic colitis is multicausal inflammatory bowel disease, which affects mostly elderly, particularly women. It a cause of chronic, watery diarrhea. MC usually presents macroscopically normal, thus diagnosis requires colonoscopy histological examination colonic biopsies. doesn’t increase risk colon cancer. However, it leads to impaired patients’ quality life reduced...

The array format has revolutionised biomedical experimentation and diagnostics, enabling ordered high-throughput analysis. During the past decade, classic solid phase substrates, such as microtitre plates, membrane filters and microscopic slides, were turned into high-density, chip-like structures. The concept of the arrayed library was central to this development which now extends from DNA to ...

Microscopic hematuria is a common finding in patients presenting to both primary care doctors as well as urologists. Sources of microscopic hematuria include infection, stones, inflammatory disorders as well as cancer of the genitourinary tract, particularly urothelial cancer. A primary focus in the urologic workup of hematuria is to rule out cancer. This is done using radiographic studies as w...