a multiple linear regression model is proposed to calculate capacity factor of  analytes using structural features computed using hyperchem software. the  chemical descriptors of analytes were computed using hyperchem software and  regressed against the experimental capacity factors of analytes collected from the  literature. the absolute average percentage deviation (aard) and individual perce...

Migration of charged compounds in micellar electrokinetic chromatography (MEKC) is based on micellar solubilization as well as electrophoretic migration. Consequently, the migration behaviour of these compounds can be described with a retention model or a mobility model. Both models are discussed and evaluated for the migration behaviour of monovalent weak acids in a sodium dodecyl sulphate mic...

A simple and sensitive on-chip preconcentration, separation, and electrochemical detection (ED) method for the electrophoretic analysis of food dyes was developed. The microchip comprised of three parallel channels: the first two are for the field-amplified sample stacking (FASS) and subsequent field-amplified sample injection (FASI) steps, while the third one is for the micellar EKC with ED (M...

The report of methicillin-resistant Staphylococcus aureus (MRSA) encoding a divergent mecA gene in 2011 was highly significant. This homologue, designated mecC, poses diagnostic problems with the potential to be misdiagnosed as methicillin-sensitive S. aureus, with important potential consequences for individual patients and for the surveillance of MRSA. mecC MRSA have now been reported from 13...

We report on the application of sweeping-MEKC, for the first time, using the Environmental Protection Agency Method 8330 stock standard (a mixture of 14 explosives). The use of a traditional MEKC mode provided the LODs (at S/N=3) ranging from 1.5 to 2.9 microg/mL for the 14 explosives standards, which were improved by as low as 3.1-6.5 ng/mL when a sweeping-MEKC technique was used. A set of 21 ...

Since its introduction capillary electrophoresis has shown great potential in areas where electrophoretic techniques have rarely been used before, including here the analysis of pharmaceutical substances. The large majority of pharmaceutical substances are neutral from electrophoretic point of view, consequently separations by the classic capillary zone electrophoresis; where separation is base...

A simple method for the routine determination of quercetin in biological samples was developed. The method consists of hydrolysis of bonded quercetin, its isolation and preconcentration on solid-phase extraction (SPE) column and a final analytical step using micellar electrokinetic capillary chromatography. The working range, linear range, the limit of quantification, and the measurement uncert...