purpose: to recognize affective factors in delivering x-ray contrast agents (which have high atomic number) via gallium carrier to liver or lymphatic neoplasm cells.   materials and methods: since uptake of gallium by liver has been reported in numerous researches, it was bonded with a contrast media (metrizoate). x-ray imaging was done to determine geometric features of liver.   results: radio...

Cerebral computed tomography was performed in 60 patients referred for pre- and postcontrast scanning. The patients were randomly sampled with a nonionic contrast medium, iohexol, and an ionic contrast medium, sodium metrizoate. No complications were seen, and the adverse effects, usually a feeling of warmth, were very minor with both contrast media, but iohexol caused less discomfort than sodi...

  Purpose: To recognize affective factors in delivering X-ray contrast agents (which have high atomic number) via gallium carrier to liver or lymphatic neoplasm cells.   Materials and Methods: Since uptake of gallium by liver has been reported in numerous researches, it was bonded with a contrast media (metrizoate). X-ray imaging was done to determine geometric features of liver.   Results: Rad...

Intracoronary administration of contrast materials causes myocardial depression which is related to serveral physiochemical properties of the contrast solution. The role of variations in ambient calcium ions (Ca++) in mediating this effect was evaluated in 19 anesthetized dogs. Sodium meglumine diatrizoate caused decreases in left ventricular peak systolic pressure (LVPSP),-12.6 +/- 3.2%, and d...

1. Iodinated density gradient media a historical perspective 1a. Metrizoate and diatrizoate In the nineteen-sixties, Nyegaard (later Nycomed) in Oslo began producing X-ray imaging agents that were derivatives of tri-iodobenzoic acid. Metrizoate (produced under the trade name IsopaqueTM) was one of the early versions of these tri-iodobenzoic acid derivatives (Figure 1). At about the same time, c...

Numerous iodide-containing compounds are used in radiographic contrast media. Severe, untoward reactions to these agents are of two types, cardiorespiratory collapse and, less commonly, anaphylactic reactions (Goodman and Gilman, 1965). This paper reports a case of severe laryngeal oedema which developed as an allergic reaction to sodium metrizoate 75 per cent (Triosil) administered during card...