intravenous glucocorucoid pulse therapy is a common treatment for immunologically origin diseases but it can not be considered a completely bening treatment.the effects of long term administration of glucocorticoids on calcium and phosphorus metabolism are week known ,but is less in known about the effect of pluse therapy.the purpose of this study was to investigate the effect of methylpredn...

Case Report The patient became ill when she was 3 years old. She had fever, rash and artralgia and pericarditis. After examination in hospital she was diagnosed sJIA. She took glucocorticosteroids 1 mg/kg daily per os, methylprednisolone 10 mg/kg IV, No3, and MTX 10mg/m2/week with positive results. She took that therapy during 2 years. When the dose of GC decreased she had flares (fever, rash, ...

patients and methods this cross-sectional study on 71 patients with ms was carried out between 2010 and 2012, in an iranian population. demographic and pharmacological variables were recorded in d-base. statistical analyses were performed using spss for windows. results the females/males sex ratio within the study population was 3.17: 1. the mean age of females was 32.2 years old (range 20 - 45...

conclusions corticosteroid pulse therapy in spms was effective in inflammatory process, but could not postpone or decline the neurodegenerative process and besides the imposing side effects could not result in significant improvement in edss and mri plaques number in long term. patients and methods a double blind randomized controlled clinical trial was performed on 71 patients with spms referr...

Method 34 year old male patient with severe acute respiratory failure was admitted to ICU. The patient was hospitalised with progressively worsened fever, coughing and dyspnoea lasting for one week. Severe pneumonia was first considered and antibiotics were started (levofloxacin, vancomycin) empirically and O2 was given through nasal canula. The clinic progressed to severe dyspnea in hours and ...

       We are presenting a case illustrating atrial fibrillation (AF) following the use of methylprednisolone in a patient with pelvic and femur fracture. A 48- year- old man with no significant past medical history, was admitted to the emergency department after injury in a car accident. He suffered a multiple bone fracture with chief complaints of pain and shortness of breath. He was transfer...

PURPOSE Mycoplasma pneumoniae (M. pneumoniae) is one of the most common causes of community-acquired pneumonia in children. The clinical course is typically self-limited and benign; however, rare cases of severe pneumonia can develop despite appropriate antibiotic therapy. We studied the effects of methylprednisolone pulse therapy on severe refractory M. pneumoniae pneumonia in children. METH...

BACKGROUND The aim was to assess whether women with a pregnancy of unknown location (PUL) can be safely excluded from potentially unnecessary multiple clinic visits. METHODS A single-visit protocol was developed based upon data from 200 consecutive PULs. PULs were divided into groups according to the probable risk of ectopic pregnancy. Those PULs with an initial serum progesterone < or =10 nm...