Methanol poisoning results in neurological complications including visual disturbances, bilateral putaminal hemorrhagic necrosis, parkinsonism, cerebral edema, coma, or seizures. Almost all reported cases of methanol poisoning are caused by oral ingestion of methanol. However, recently there was an outbreak of methanol poisoning via non-oral exposure that resulted in severe neurological complic...

Methanol poisoning is an uncommon but an extremely hazardous intoxication. Since methanol is a versatile fuel and is having increasing usage in an energy-conscious society, a high index of suspicion and swift laboratory confirmation is essential in managing this poisoning. Methanol poisoning may occur in sporadic or epidemic circumstances. Chronic exposure may occur in the occupational setting....

Poisonings from toxic alcohols, such as methanol (MeOH) are a serious toxicological concern worldwide. In an endemic methanol poisoning in 2012 in the Czech Republic 121 subjects had consumed adulterated beverages and 41 died from the poisoning. An additional 20 subjects still suffer from visual/CNS sequelae [1]. In addition to mass poisonings single cases of methanol poisoning had been publish...

This discussion will highlight the following 9 specific points that related to metabolic acidosis caused by various toxins. The current recommendation suggests that alcohol dehydrogenase inhibitor fomepizole is preferred to ethanol in treatment of methanol and ethylene glycol poisoning, but analysis of the enzyme kinetics indicates that ethanol is a better alternative. In the presence of a mode...

background: world health organization (who) reported continuous increase of alcohol consumption in southeast asian region. on social and religious ground, open alcohol consumption is banned in bangladesh though incidence of acute methanol intoxication is seriously increasing. unfortunately, apart from who report (2004) there is no available epidemiological and clinical data in bangladesh. this ...

A 22-year-old male presented with acute onset vomiting, diarrhea, abdominal pain and altered sensorium. He had a history of acute alcohol intake (locally made with solvent) a day prior to the presentation. Biochemical investigations revealed severe metabolic acidosis. Diagnosis of methanol poisoning was made on the basis of history and biochemical abnormality. Magnetic resonance imaging (MRI) d...

methanol is responsible for a life-threatening poisoning. fomepizole, a potent alcohol dehydrogenase inhibitor, is an efficient and safe antidote that prevents or reduces toxic methanol metabolism. although no study has compared its efficacy with ethanol, fomepizole is recommended as a first-line antidote. treatment should be started as soon as possible, based on history and initial findings in...

background: in iran, methyl alcohol poisoning rarely occurs accidentally and usually occurs through abuse of contaminated ethanol. however, with proper and timely treatment complications and mortality of methanol poisoning can be prevented. in this study, the epidemiological profile of methanol poisoning in the iranian society was investigated. methods: in this prospective cross-sectional study...

background consumption of home-distilled alcohol may lead to epidemic or sporadic cases of severe acute methanol poisoning. the difficulty of establishing strict indications for hemodialysis in acute methanol poisoning is a widely recognized issue. materials and methods the determination of the clinical, especially hemodialysis, and para clinical factors influencing patient survival in 46 acute...