نتایج جستجو برای: metalloprotein

تعداد نتایج: 408  

2001
Brian R Gibney

Metalloprotein and redox protein design are rapidly advancing toward the chemical synthesis of novel proteins that have predictable structures and functions. Current data demonstrate a breadth of successful approaches to metallopeptide and metalloprotein design based on de novo, rational and combinatorial strategies. These sophisticated synthetic analogs of natural proteins constructively test ...

Journal: :Journal of Materials Chemistry C 2021

Correction for ‘Electrochemical gating enhances nearfield trapping of single metalloprotein junctions’ by Albert C. Aragonès et al. , J. Mater. Chem. C 2021, DOI: 10.1039/d1tc01535d.

Journal: :YAKUGAKU ZASSHI 1965

Journal: :Science 1940
D Woodman

Featured Keynote Speaker Prof. Brian Gibney CUNY Graduate Center While DNA is the blueprint for the cell, it is the proteins that do the bulk of the work. About 30% of proteins require metal ions for proper function and their dysfunction leads to human disease. The Gibney Lab takes a constructive approach toward understanding metalloprotein structurefunction relationships. Using inorganic chemi...

2016
Sarah E. J. Bowman Jennifer Bridwell-Rabb Catherine L. Drennan

Metal ions and metallocofactors play important roles in a broad range of biochemical reactions. Accordingly, it has been estimated that as much as 25-50% of the proteome uses transition metal ions to carry out a variety of essential functions. The metal ions incorporated within metalloproteins fulfill functional roles based on chemical properties, the diversity of which arises as transition met...

Journal: :Journal of Materials Chemistry C 2021

Metalloprotein junctions are used as model systems in the field of molecular bioelectronics to mimic electronic circuits. The junction lifetime increase achieved with electrochemical nearfield trapping enables thorough characterisation.

Journal: :Acta Crystallographica Section A Foundations of Crystallography 2000

Journal: :Acta Crystallographica Section A Foundations and Advances 2018

2012
Magali Lorenzi Léa Sylvi Guillaume Gerbaud Elisabetta Mileo Frédéric Halgand Anne Walburger Hervé Vezin Valérie Belle Bruno Guigliarelli Axel Magalon

Molecular recognition is central to all biological processes. Understanding the key role played by dedicated chaperones in metalloprotein folding and assembly requires the knowledge of their conformational ensembles. In this study, the NarJ chaperone dedicated to the assembly of the membrane-bound respiratory nitrate reductase complex NarGHI, a molybdenum-iron containing metalloprotein, was tak...

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