A complete characterization of locally primitive normal Cayley graphs of metacyclic groups is given. Namely, let Γ = Cay(G,S) be such a graph, where G ∼= Zm.Zn is a metacyclic group and m = p1 1 p r2 2 · · · p rt t such that p1 < p2 < · · · < pt. It is proved that G ∼= D2m is a dihedral group, and val(Γ ) = p is a prime such that p|(p1(p1 − 1), p2 − 1, . . . , pt − 1). Moreover, three types of ...