نتایج جستجو برای: metabolomics

تعداد نتایج: 12395  

آقارضایی, نیلوفر, ارجمند, بابک, رضادوست, حسن, زمانی کوخالو, سعیده, مرزبانی, رضوان, گیلانی, کامبیز,

Infertility influences an estimated 20% of couples worldwide. The factors that can affect the fertility potential are equally distributed between men and women. Despite extensive research in male infertility, the etiology in majority of infertile men is unknown. In 2010, there was an opinion published in Nature asking a selection of leading researchers and policy-makers about what their future ...

Various mesenchymal stem cells as easily accessible and multipotent cells can share different essential signaling pathways related to their stemness ability. Understanding the mechanism of stemness ability can be useful for controlling the stem cells for regenerative medicine targets. In this context, OMICs studies can analyze the mechanism of different stem cells properties or stemness ability...

Metabolomics, is a comprehensive measure of small metabolites (<1500 Da), which has attracted enormous attention in the last two decades. Metabolomics, in particular investigates unique biochemical fingerprints left behind by specific cellular processes, which represent the metabolic status. Exercise metabolism researchers have started to use this method since 2007. Metabolomics has been used t...

Journal: :international journal of reproductive biomedicine 0
negar ghazi mohammad arjmand ziba akbari ali owsat mellati hamid saheb-kashaf zahra zamani

background: so far, non-invasive diagnostic approaches such as ultrasound, magnetic resonance imaging, or blood tests do not have sufficient diagnostic power for endometriosis disease. lack of a non-invasive diagnostic test contributes to the long delay between onset of symptoms and diagnosis of endometriosis. objective: the present study focuses on the identification of predictive biomarkers i...

Journal: :journal of paramedical sciences 0
afsaneh arefi oskouie faculty of paramedical sciences, department of basic sciences, shahid beheshti university of medical sciences, tehran, iran salman taheri chemistry and chemical engineering research center of iran, tehran, iran.

metabolomics studies provide useful information about health and disease status. metabolite based investigations on various cancers is a powerful approach to diagnosis, prognosis and therapy of cancer diseases. recently by using advanced analytical techniques such as nmr and ms and its hyphenation methods, global metabolic profiling of diseases has been possible. it is predictable that internat...

Background: Chronic kidney disease (CKD), characterized by progressive loss of renal function, is becoming a growing problem in the general population. New analytical technologies such as “omics”-based approaches, including metabolomics, provide a useful platform for biomarker discovery and improvement of CKD management. In metabolomics studies, not only prediction accuracy is ...

Journal: :gastroenterology and hepatology from bed to bench 0
akram safaei afsaneh arefi oskouie seyed reza mohebbi mostafa rezaei-tavirani mohammad mahboubi maryam peyvandi

metabolome analysis is used to evaluate the characteristics and interactions of low molecular weight metabolites under a specific set of conditions. in cirrhosis, hepatocellular carcinoma, non-alcoholic fatty liver disease (nafld) and non-alcoholic steatotic hepatitis (nash) the  liver  does not function thoroughly due to long-term damage. unfortunately the early detection of cirrhosis, hcc, na...

2013
Reza M Salek Kenneth Haug Christoph Steinbeck

With ever-increasing amounts of metabolomics data produced each year, there is an even greater need to disseminate data and knowledge produced in a standard and reproducible way. To assist with this a general purpose, open source metabolomics repository, MetaboLights, was launched in 2012. To promote a community standard, initially culminated as metabolomics standards initiative (MSI), COordina...

Journal: :Journal of integrated OMICS 2013
Steven Halouska Bo Zhang Rosmarie Gaupp Shulei Lei Emily Snell Robert J Fenton Raul G Barletta Greg A Somerville Robert Powers

Over the past decade, metabolomics has emerged as an important technique for systems biology. Measuring all the metabolites in a biological system provides an invaluable source of information to explore various cellular processes, and to investigate the impact of environmental factors and genetic modifications. Nuclear magnetic resonance (NMR) spectroscopy is an important method routinely emplo...

2010
Lloyd W Sumner

Metabolomics is an extension of the omics concept and experimental approaches. However, is metabolomics just another trendy omics fashion perturbation or is metabolomics actually delivering novel content and value? This article highlights some recent advances that definitely support the role of plant metabolomics in the movement toward greener pastures.

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