Since 1974 we have treated 118 patients suffering from unilateral and bilateral (two patients) Morbus Meniere with intratympanal applications of gentamicin-sulfate. In contrast to earlier attempts using this method, we did not try to destroy the vestibular apparatus, but taking into our considerations the recent findings about the pathophysiological mechanism of Morbus Meniere, only to damage t...

Our experience with 102 patients having superior semicircular canal dehiscence confirm that the clinical manifestations of the disease are very diverse; we also identified 3 patients who showed Meniere-like symptoms. Clinical examination during an acute vertigo attack of a patient with Meniere disease for several years and whom we subsequently diagnosed as having large superior semicircular can...

Introduction The nature and extent of membrane damage encountered in Meniere disease remains unexplained. Pressure-induced membrane stress may underlie the characteristic hydropic distention. Analysis of stress in the several vestibular chambers may offer insight into the nature and progression of Meniere disease. Objective Membrane stress levels will be assessed by constructing a specific mode...

Endolymphatic hydrops (can only be diagnosed by postmortem histopathological examination of temporal bone) Immunological Mechanism Genetic Predisposition (AD inheritence) Viral Predisposition not proved Vascular Etiology (Migraine Association) (VIG viral vascular, immunological, genetic) RUPTURE THEORY Periodic ruptures of the membranous labyrinth, which result in leakage of the potassium-rich ...

BACKGROUND As a parameter for the evaluation of the vestibular evoked myogenic potential (VEMP), amplitude has been used clinically. However, the significance of latency has not been considered. OBJECTIVE To clarify the diagnostic value of latencies of the VEMP. DESIGN We reviewed records of the VEMP of patients with various diseases and compared them with records of healthy volunteers. S...