BACKGROUND Melasma is a chronic, acquired hyperpigmentation disease on sun-exposed areas of the skin, which affects patients' quality of life. OBJECTIVE To assess the impact on the quality of life of women living in Florianópolis, Brazil, through questionnaire (MelasQol), and investigate the clinical aspects and risk factors for melasma, correlating them with the MelasQol scores. METHODS Th...

BACKGROUND Although asymptomatic, melasma inflicts significant impact on quality of life. MELASQoL is the main instrument used to assess quality of life associated with melasma, it has been validated in several languages, but its latent dimensional structure and psychometric properties haven´t been fully explored. OBJECTIVES To evaluate psychometric characteristics, information and dimensiona...

Melasma has significant emotional and psychological effects. These repercussions can be measured using general measures of skin disease. SKINDEX-16 was used in a pilot study (1) to show a significant impact on health-related quality of life (HRQoL) and a correlation with disease severity measured by MASI (Melasma Area Severity Index) (2). A melasma-specific scale, the Melasma Quality of Life Sc...

BACKGROUND Melasma is a common chronic and relapsing acquired dyschromia. Skin microneedling was reported resulting sustained long-term improvement of recalcitrant melasma, however, the exact mechanism that promotes this skin lightening is not known. This study aimed to investigate clinical and histologic alterations promoted by skin microneedling in facial melasma. METHODS Open pilot trial i...

Introduction: Melasma is the most common cause of facial melanosis and one diseases presenting to Dermatology department. It can lead psychological emotional distress for patients hamper their quality life. So, this study was done assess life among with melasma so that need couseling these could be assessed along medical treatment. Materials Methods: This a hospital based cross sectional 205 cl...

Exposure to the sun, ultraviolet radiation, and oxidative stress are the chief etiologic factors responsible for melasma. The ingredients of Korean red ginseng powder, which include ginsenoside and phenolic compounds, have antioxidative effects and reduce ultraviolet B-induced pigmentation. This study was designed to evaluate the effectiveness and safety of Korean red ginseng powder in patients...

This article focuses on developments in pigmentary disorders that extend dermatologists' understanding of the field. Areas that are reviewed include the basic biochemistry, pharmacology, and physiology of the melanocortin system; melanosome development; genetic diseases associated with pigmentary disorders; pigmentary disorders secondary to systemic disease; drug-induced hyperpigmentation; envi...