background:non-melanoma skin cancer (nmsc), the most prevalent types being squamous cell carcinoma (scc) and basal cell carcinoma (bcc), is the most common type of malignancy in human beings. these neoplasms are more frequent in the elderly and fair skinned people and mainly occur on sun-exposed sites of the body. ultraviolet b (uvb) has a well-known effect in induction and promotion of growth ...

Background:Non-Melanoma Skin Cancer (NMSC), the most prevalent types being Squamous Cell Carcinoma (SCC) and Basal Cell Carcinoma (BCC), is the most common type of malignancy in human beings. These neoplasms are more frequent in the elderly and fair skinned people and mainly occur on sun-exposed sites of the body. Ultraviolet B (UVB) has a wel...

Differentiating melanocytic from non-melanocytic (MnM) skin lesions is the first and important step required by clinical experts to automatically diagnosis pigmented skin lesions (PSLs). In this paper, a new clinically-oriented expert system (COE-Deep) is presented for automatic classification of MnM skin lesions through deep-learning algorithms without focusing on preor post-processing steps. ...

Background: Malignant melanoma is the most aggressive form of skin cancer. In contrast to other tumors, the role of estrogen in the initiation and progression of melanoma remains unclear. The aim of this study was to evaluate estrogen receptor beta protein expression in human melanoma tissues and in the benign melanocytic lesions. Method: Twenty-one patients, 11 with cutaneous melanoma and 10 w...

BACKGROUND Computer-aided diagnosis (CADx) software that provides a second opinion has been widely used to assist physicians with various tasks. In dermatology, however, CADx has been mostly limited to melanoma or melanocytic skin cancer diagnosis. The frequency of non-melanocytic skin cancers and the accessibility of regular digital macrographs have raised interest in developing CADx for broad...

Background: Non-melanocytic skin cancers (NMSC) including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are mostly induced by long life sun ultraviolet radiation (UVR). Although many etiological factors are known in skin cancer, the role of sunlight is the most prominent. Khuzestan is one of the southern provinces of Iran, which has sunny sky and long summer. So it is presumed th...

BACKGROUND Melanoma is the major cause of skin cancer death worldwide. Parkinson's disease is a neurodegenerative disorder that is caused by mutation of alpha-synuclein or other genes. Importantly, epidemiological studies have reported co-occurrence of melanoma and Parkinson's disease, suggesting that these two diseases could share common genetic components. METHODOLOGY/PRINCIPAL FINDINGS Rec...

Malignant melanoma is the deadliest form of skin cancer, known for its drug resistance and high metastatic potential. Deregulated PI3 and mitogen activated protein (MAP) kinase pathways promote early melanocytic lesion development and confer drug resistance. No agent exists to target these deregulated pathways to prevent cutaneous noninvasive melanocytic cells or invasive melanomas from develop...

The main cause of skin cancer is the ultraviolet radiation sun. It spreads quickly to other body parts. Thus, early diagnosis required decrease mortality rate due cancer. In this study, an automatic system for Skin Lesion Classification (SLC) using Non-Subsampled Shearlet Transform (NSST) based energy features and Support Vector Machine (SVM) classifier proposed. At first, NSST used decompositi...