EWSR1, a protein whose role in meiosis was not previously clarified detail, binds to both the recombination regulator PRDM9 and phosphorylated meiosis-specific cohesin pREC8 male meiotic cells is essential for promoting PRDM9-dependent histone methylation normal progress.

The germ cell nuclear factor (GCNF) is a member of the nuclear receptor super family of transcription factors. GCNF expression during gastrulation and neurulation is critical for normal embryogenesis in mice. GCNF represses expression of the POU domain transcription factor Oct4 during mouse post-implantation development in vivo. Oct4 is thus down-regulated during female gonadal development, whe...

A long-standing tradition uses strings of poppit beads different colors to model meiosis, especially show how segments paired homologous chromosomes are recombined. Our use orthodontic latex bands cohesion sister chromatids, and plastic coffee stirrers as microtubules, extends what can normally be achieved with ‘standard’ commercial kits beads, so emphasizing the importance four key...

Oroxylum indicum (L.) Kurz a well know and pharmaceutically explored medicinal plant of the family Bignoniaceae but in context cytological work, meagre information is available on same plant. During present investigation six accessions O. were studied for understanding male meiosis related events using standard techniques. Although, meiotic course was found to be regular, anomalies such as chro...

If the concepts used in curriculum, textbooks, classroom teaching, and assessment are not consistent, students may have difficulty understanding of science correctly this lead to formation misconceptions. The purpose study is measure alignment by analyzing semantic networks student with respect contents on meiosis as covered Life Science I. network method using NetMiner 4.0 program was applied....

introduction: in this study in vitro maturation, resumption of meiosis and development of immature mouse oocytes in the presence of cysteamine was evaluated. meterial and methods: immature oocytes recovered from nmri mouse strain (4-6 weeks) were categorized in three experimental and one control group. the control included 345 immature oocytes which were matured in mem medium contain 5% fcs. in...

Spotted scat ( Scatophagus argus ) is an important mariculture fish that of great economic significance in East and Southeast Asia. To date, there are no studies on ovary development regulation S. . Herein, the transcriptome profiles at different stages were constructed, genes pathways potentially involved secondary follicle growth identified. A total 25,426 detected by sequencing mRNAs from li...

During meiosis, two consecutive rounds of chromosome segregation yield four haploid gametes from one diploid cell. The Polo kinase Cdc5 is required for meiotic progression, but how Cdc5 coordinates multiple cell-cycle events during meiosis I is not understood. Here we show that CDC5-dependent phosphorylation of Rec8, a subunit of the cohesin complex that links sister chromatids, is required for...