conclusions despite the progress made in medicine, meconium aspiration syndrome is still one of the causes of newborn infants’ mortality. the mortality and morbidity rates can be reduced by improvement in perinatal care, prevention of post term delivery, timely caesarean and effective neonatal resuscitation at birth. results sixty-three newborn infants, diagnosed with meconium aspiration syndro...

Perhaps the most significant changes in airway management over the recent years have been in the management of an infant delivered through meconium- stained amniotic fluid( MSAF). MSAF occurs in approximately 10℅ to 20℅ of all deliveries and increases to over 30℅ in deliveries after 42 weeks gestation. Meconium aspiration syndrome ( MAS) occurs in about 2℅ to 5℅ of these cases with a high morta...

BACKGROUND Meconium aspiration syndrome is a disease of the newborn mature or post mature. The acute pulmonary consequences can be extremely severe. In the few studies of the long-term pulmonary sequelae, it seems that certain children surviving meconium aspiration syndrome keep an obstructive syndrome. The aim of our study was to assess long term respiratory residual damage from meconium aspir...

Meconium stained amniotic fluid (MSAF) complicates delivery in approximately 8% to 25% of live births. Approximately 5% of neonates born through MSAF develop meconium aspiration syndrome (MAS), and approximately 50% of these infants require mechanical ventilation. Meconium aspiration before or during birth can obstruct airways, interfere with gas exchange and cause severe respiratory distress [...

device. Abstract Aspiration of meconium produces a syndrome characterized by hypoxia, hypercapnia, and acidosis. Perinatal hypoxia, acute airway obstruction, pulmonary inflammation, pulmonary vasoconstriction, pulmonary hypertension, and surfactant inactivation all play a role in the pathogenesis of meconium aspiration syndrome (MAS). Most aspiration of meconium probably occurs before birth. Fo...

In the years 1977-82, 43 infants with the meconium aspiration syndrome (MAS) were managed at the Department of Paediatrics of Turku University Central Hospital (TUCH), Finland. Among 5,353 deliveries in one year the incidence of meconium staining was 8.7%. By extrapolation, the incidence of meconium aspiration in all newborns is approximately 0.13%. The mean duration of the pregnancies was 39.2...

We agree that the passage of meconium in utero is not always due to intrauterine asphyxia and it may be a purely physiological event due to increasing maturity of the fetus. However, a bacterial endotoxin has been recently implicated in "causing the preterm labor and passage of meconium in utero(3). It is to be emphasized that only those neonates who have respiratory\distress with radiological ...

OBJECTIVE To test the hypothesis that total liquid ventilation enables a more effective and better tolerated lavage than a bronchoalveolar lavage performed with diluted surfactant in a newborn ovine model of severe acute meconium aspiration syndrome. DESIGN Prospective, randomized, interventional study. SETTING Animal research laboratory at the Faculté de médecine et des sciences de la sant...