objective: various approaches have been offered for resolution of pain resulting from spinal cord injuries. one approach is the use of herbal and natural products. in the present research, as a preliminary study, we investigate the effect of crocin on chronic pain induced by contusion in the rat spinal cord (sci). methods: we randomly divided female wistar rats into five groups. groups i and ii...

The present study was performed to observe the time course of behavioral signs of painful sensations in sciatic neurectomy animal model and to test the effects of sympathectomy and saphenous nerve section on these behavioral signs. Sciatic nerve was ligated and cut at the mid-thigh level under gaseous anesthesia. The application of von Frey filaments to the medial plantar surface of foot reveal...

by Let QU denote the class of anal>-tic functions which are regular and unbounded in ;zI < 1. According io D. GAIER and IV. MEYER-K~NIG [I] we call the radius Rq defined bJ+ x = r&c'!, 0 5 r <: 1 singular for f(x), if f(z) is unbounded in any sector /zI < 1, pl-E < arg 2 < < p7 + e Fith E > 0. h radius which is not singular for f(z) is called regular for f(z). In [l] it has been shown that if f...

Treatment of neuropathic pain is still a major challenge because of its noresponsiveness to most available pharmacotherapy. Curcumin has been reported to play an active role in the treatment of various neurological disorders, such as neuropathic pain. In this study, the role of curcumin has been evaluated in pain behavioral responses of chronic Constriction injury (CCI) in rat. In this experime...

Molecular and behavioral evidence suggests that acid-sensing ion channels (ASICs) contribute to pain processing, but an understanding of their precise role remains elusive. Existing ASIC knock-out mouse experiments are complicated by the heteromultimerization of ASIC subunits. Therefore, we have generated transgenic mice that express a dominant-negative form of the ASIC3 subunit that inactivate...

introduction: intracerebroventricular (i.c.v.) injection of streptozotocin (stz) to rodents has been reported as an appropriate model for sporadic dementia of alzheimer&apos;s type (sdat), characterized by a progressive impairment of memory. however, very little or nothing is known about non-cognitive behavioral effects in the stz model. this study was carried out in order to show the protectiv...

structural steel sections are mainly used in beams and columns of building frames. iran national steel industrialgroup is among the oldest and largest producers of beams in iran. it has two beam production lines, namely line630 and line 650. in this study, the mechanical properties of manufactured beams in these production lines werecompared. based on the t-test results, the elongation is signi...

hydroalcoholic extract of pycnocycla spinosa has spasmolytic action in vitro . at oral dose of 250 m g/kg it inhibits castor oil induced diarrhea in mice. if p. spinosa extract has no serious adverse effect, it would be a good alternative medicine for treatment of diarrhoea and abdominal spasm. in this research, overall systemic effect of p. spinosa extract on mice behavior and reaction was inv...