Objective: Measurement of glomerular filtration rate (GFR) is the best determinant in assessment of kidney function for diagnostic and therapeutic purposes. As extremely accurate methods of GFR measurement (i.e. Inulin clearance) are expensive and Time-consuming and due to limitations of the 24 hour urine collection method, some formula have been developed for the GFR measurement. Here we have ...

The ability of the Modification of Renal Disease (MDRD) equation to predict GFR when compared with multiple other prediction equations in healthy subjects without known kidney disease was analyzed. Between May 1995 and December 2001, a total of 117 healthy individuals underwent (125)I-iothalamate or (99m)Tc-diethylenetriamine-pentaacetic acid (DTPA) renal studies as part of a routine kidney don...

Introduction: We intended to assess the accuracy of re-expressed Modification of Diet for Renal Disease (MDRD) and Cockcroft-Gault (CG) equations to estimate glomerular filtration rate (GFR) in chronic kidney disease in two different etiologies of acute renal failure (ARF): acute tubular necrosis (ATN) and acute glomerulonephritis (AGN). Methods: Patients admitted for ARF or the patients compl...

BACKGROUND Two modifications of the MDRD equation [the Mayo Clinic (MC) equation and Rule's refitted (RR) MDRD formula] were proposed to overcome disadvantages of the original MDRD formula to calculate glomerular filtration rate (GFR). Additionally, a correction factor for the original MDRD formula has been introduced to adapt this formula to creatinine values measured by the isotope-dilution m...

The Modification of Diet in Renal Disease (MDRD) equations provide a rapid method of assessing GFR in patients with chronic kidney disease (CKD). However, previous research indicated that modification of these equations is necessary for application in Chinese patients with CKD. The objective of this study was to modify MDRD equations on the basis of the data from the Chinese CKD population and ...

OBJECTIVE The Cockcroft-Gault formula is recommended for the evaluation of renal function in diabetic patients. The more recent Modification of Diet in Renal Disease (MDRD) study equation seems more accurate, but it has not been validated in diabetic patients. This study compares the two methods. RESEARCH DESIGN AND METHODS In 160 diabetic patients, we compared the Cockcroft-Gault formula and...

BACKGROUND the Modification of Diet in Renal Disease (MDRD) method of renal function estimation has not been extensively assessed in elderly patients. We needed to assess which renal function estimate was most suited for drug dose estimation in our population. METHOD we compared MDRD with an optimised version of the Cockcroft-Gault (CG(opt)) method in a hospital population, using gentamicin c...

OBJECTIVE To compare the bias, absolute bias, precision and accuracies between the equations, viz., CKD-EPI (Scr), CKD-EPI (Scys) and MDRD in Indian patients with type 2 diabetes. METHODS 198 patients who underwent 24 h urinary collection for assessing kidney function between November 2014-January 2015 were included. Cohen's κ coefficient, Bland-Altman plot were calculated between estimated k...

BACKGROUND Renal dysfunction is common in HIV-positive patients, and guidelines suggest regular monitoring of renal function with estimated glomerular filtration rate (eGFR) and urinalysis. It is unknown whether Chronic Kidney Disease Epidemiological Collaboration (CKD-EPI) or Modification of Diet in Renal Disease (MDRD) provide better estimates of glomerular filtration rate (GFR) in this popul...

objective: measurement of glomerular filtration rate (gfr) is the best determinant in assessment of kidney function for diagnostic and therapeutic purposes. as extremely accurate methods of gfr measurement (i.e. inulin clearance) are expensive and time-consuming and due to limitations of the 24 hour urine collection method, some formula have been developed for the gfr measurement. here we have ...