introduction: the purpose of the present study was to evaluate the effect of prednisolone on the sensitivity of bone scanning to detect the simulated closed fracture in the rat tibia.  methods: a total number of forty eight adult, male nmri rats randomly assigned into two parts, one part for 4 and other for 8 weeks experiments. each part has been divided into four groups, one group not receivi...

Introduction: Extraosseous accumulation of 99mTc – methylene diphosphonate (MDP) may be due to neoplastic, dystrophic, hormonal, inflammatory, ischemic, traumatic or excretory disorders. 99mTc-MDP incidental thyroid uptake is not frequent and is possibly caused by the presence of dystrophic or metastatic calcification, biopsy procedure and presence of beni...

The present case demonstrates a diffuse intense hepatic and, to a lesser degree, spleen, Tc-99m MDP uptake on a routine bone scintigraphy resembling liver-spleen imaging. A 49-year-old female with a history of anaplastic plasma cell tumor and suffering from bone pain was referred for bone scintigraphy to evaluate possible bone metastases. The bone scintigraphy showed diffuse hepatic and spleen ...

Incidental extra-osseous uptake of 99mTc-MDP on bone scintigraphy has been frequently reported in the literature; however, calcification of the psoas muscle is a rare condition, which has been reported on magnetic resonance (MR) and computed tomography (CT) imagings. Here we report a 67-year-old woman with acute paraplegia and low back pain who was referred for a 99mTc-MDP...

Introduction: In Islamic countries in the month of Holy Ramadan many Muslims based on their religious Legislation refuse fluid intake during the fasting time though instructed to drink after injection of Tc-99m Methylene-diphosphonates [Tc-99m MDP] used for skeletal scintigraphy. We aimed to establish whether fluid restriction in Tc-99m MDP skeletal scintigraphy has an impact on its quality. M...

introduction: in islamic countries in the month of holy ramadan many muslims based on their religious legislation refuse fluid intake during the fasting time though instructed to drink after injection of tc-99m methylene-diphosphonates [tc-99m mdp] used for skeletal scintigraphy. we aimed to establish whether fluid restriction in tc-99m mdp skeletal scintigraphy has an impact on its quality. me...

a 10-year-old boy was referred to us for evaluation of fuo accompanied with bone pain in both calves. three hours after intravenous injection of 13 mci of 99mtc-mdp, whole body scan in multiple spot views was performed. the scan showed symmetrical areas of diffusely increased tracer uptake in multiple long bones. histopathologic evaluation confirmed osteosclrosis and fibrotic changes without an...

Bone scintigraphy is a sensitive and popular method for imaging a wide array of benign or malignant skeletal abnormalities. However, the uptake of tracers used for bone scintigraphy may be observed in various extraosseous sites, thereby limiting its specificity. It is difficult to correctly localize such sites of uptake on planar bone scintigraphy alone. The addition of hybrid single-photon emi...

PURPOSE 99mTechnetium methylene diphosphonate (99mTc MDP) bone scintigraphy is currently the method of choice for the detection of bone metastases, but 18F-fluoro-deoxy-D-glucose positron emission tomography (18FDG PET) offers superior spatial resolution and improved sensitivity. We have compared 18FDG PET with 99mTc MDP bone scintigraphy in patients with skeletal metastases from breast cancer ...