This study was conducted to confirm that medium chain triglyceride (MCT) feeding itself would increase hepatic lipogenic enzyme activity without causing a lack of essential fatty acids (EFA) in the liver. Male weaning rats were fed for 11 weeks on diets containing 2% corn oil and 13% various fats: MCT, corn oil, tripalmitin or beef tallow, respectively. MCT feeding was clearly shown to increase...

Due to its unique absorption and metabolism characteristics, medium chain triglyceride (MCT) oil, consisting of fatty acids with 8-12 carbons, has been used therapeutically since the 1950s in the treatment of fat malabsorption, cystic fibrosis, epilepsy, weight control, and to increase exercise performance. Medium chain triglycerides are easily hydrolyzed in the intestines and the fatty acids a...

OBJECTIVE To determine if medium-chain triglycerides (MCTs) prevent organ injuries and mortality in rats administered endotoxin and to investigate effects of MCT on the gut. SUMMARY BACKGROUND DATA Since dietary MCTs prevent alcohol-induced liver injury by inhibiting activation of Kupffer cells in the enteral feeding model, the authors hypothesized that MCT could prevent deleterious condition...

This study was undertaken to determine the effect of medium-chain triglyceride (MCT) oil supplementation on the duration and episodes of diarrhea attacks, and specifically its effect on the clinical manifestations of patients. Seventeen children aged 6 months to 47 months old with a mean age of 19.6 months, suffering from acute diarrhea at the Pediatric Ward of the Philippine General Hospital M...

We report the case of a 43-year-old man with history of nonsurgical partial epilepsy who previously failed multiple trials of antiepileptic drugs. Medium-chain triglycerides (MCT) were added to his regular diet in the form of pure oil. Subsequently, his seizure frequency was markedly reduced from multiple daily seizures to one seizure every four days. His seizures recurred after transient disco...

prematurity and poor weight gaining are important causes for neonatal hospitalization. the present study aimed to investigate the role of medium-chain triglyceride (mct) oil via massage therapy as a supplementary nutritional method on the weight gain of neonatal intensive care units (nicu)-hospitalized neonates. this randomized clinical trial performed among 121 stable premature neonates hospit...

A total of 24 crossbred barrows were used in a 19-d metabolism trial to determine the effect of dietary structured triacylglycerides synthesized by the random reesterification of medium-chain triacylglycerides (MCT) and menhaden oil on growth performance, nitrogen retention, and apparent digestibilities of nitrogen, lipid, and fatty acids. Pigs were randomly assigned to four dietary treatments ...

This experiment was conducted to determine whether feeding medium-chain triglycerides (MCT) to sows during late gestation and early lactation would improve neonatal pig survival. Beginning on d 91 of gestation and continuing through d 7 of lactation, sows were fed isoenergetic (7,000 kcal of ME/d) and isonitrogenous (278 g of CP/d) amounts of either control (19% starch, 2% soybean oil), long-ch...

Metabolic syndrome is often accompanied by development of hepatic steatosis and less frequently by non-alcoholic fatty liver disease (NAFLD) leading to non-alcoholic steatohepatitis (NASH). Replacement of corn oil with medium chain triacylglycerols (MCT) in the diets of alcohol-fed rats has been shown to protect against steatosis and alcoholic liver injury. The current study was designed to det...