The University of Washington Medical Cyclotron Facility (UWMCF) is built around a Scanditronix MC50 compact cyclotron that was commissioned in 1984 and has been in continual use since. Its primary use is in the production of 50.5 MeV protons for fast neutron therapy. While this proton energy is too low for clinical proton therapy, it is ideal for proton therapy research in small animal models. ...

A systematic study with a series of irradiation tests was performed for the forward resistive plate chambers (RPCs) of the Compact Muon Solenoid (CMS) in the Large Hadron Collider (LHC) experiment. Small double-gap RPCs were manufactured and tested by the gamma rays emitted from a 200mCi Cs source at Korea University and by the fast neutrons provided by the MC50 proton cyclotron at the Korea In...

The previously determined nucleotide sequence of the porA gene, encoding the class 1 outer membrane protein of meningococcal strain MC50, has been used to clone and sequence the porA gene from two further strains with differing serosubtype specificities. Comparison of the predicted amino acid sequences of the three class 1 proteins revealed considerable structural homology with major variation ...

From the aerial parts of Gutierrezia microcephala (Asteraceae), four oxyflavones were isolated, namely 5,7,2'-trihydroxy-3,6,8,4',5'-pentamethoxyflavone (1); 5,7,4'-trihydroxy-3,6,8-trimethoxyflavone (2); 5,7,2',4'-tetrahydroxy-3,6,8,5'-tetramethoxyflavone (3); 5,2'-dihydroxy-3,6,7,8,4',5'-hexamethoxyflavone (4), and an ent-clerodane, bacchabolivic acid (5). Compounds 1-5, the synthetic methyl ...

The Clinical Neutron Therapy System at the University of Washington Medical Center in Seattle has now treated patients with fast neutrons for 20 years. During the past three years roughly 75 % of the treatments were for salivary gland tumors, where neutron therapy is the treatment of choice. After the installation of a small dedicated cyclotron in the Nuclear Medicine department for PET isotope...

BACKGROUND Micromeria croatica (Pers.) Schott is an aromatic plant from Lamiaceae family previously found to possess potent in vitro antioxidant activity which is mainly attributed to the high level of polyphenolic substances. The aim of this study was to investigate the hepatoprotective activity and possible underlying mechanisms of Micromeria croatica ethanolic extract (MC) using a model of c...

The formation mechanism of empty and metal-containing fullerene was studied through MD (molecular dynamics) simulations and FT-ICR (Fourier transform ion cyclotron resonance) mass spectroscopy of laser vaporized carbon cluster. Multi-body classical potential functions for metal-carbon and metal-metal interactions were constructed based on DFT (density functional theory) calculations of various ...