The Drosophila gene mushroom bodies tiny (mbt) encodes a putative p21-activated kinase (PAK), a family of proteins that has been implicated in a multitude of cellular processes including regulation of the cytoskeleton, cell polarisation, control of MAPK signalling cascades and apoptosis. The mutant phenotype of mbt is characterised by fewer neurones in the brain and the eye, indicating a role o...

Thermal and antimicrobial properties of hybrid synthesized compounds were evaluated in thepresent study. Hybrid structures were synthesized via two main organic and inorganic components,namely: 2-Mercaptobenzothiazole (MBT) and sodium Montmorillonite clay (Na+-MMT). The synthesis process took place in a direct reaction, intercalation; and the resultingmaterial was characterized. Results of scan...

This paper provides an overview of Model-Based Testing (MBT) and its activities. A classification of MBT based on different criteria is also presented. Furthermore, several difficulties of MBT are highlighted in this paper. A survey that provides a detailed description of how MBT is effective in testing different quality attributes of distributed systems such as security, performance, reliabili...

In Xenopus laevis embryogenesis, fertilized eggs undergo 12 cycles of synchronous divisions and reach the stage called midblastula transition (MBT). It has long been believed that during the first 12 cycles of cleavage (pre-MBT stage), transcriptional activity of the zygotic nuclei is totally absent. However, heterogeneous mRNA-like RNA is synthesized in pre-MBT stage embryos, and exogenously-i...

MBT domain proteins are involved in developmental processes and tumorigenesis. In vitro binding and mutagenesis studies have shown that individual MBT domains within clustered MBT repeat regions bind mono- and dimethylated histone lysine residues with little to no sequence specificity but discriminate against the tri- and unmethylated states. However, the exact function of promiscuous histone m...

I n 2007, 38% of Americans used complementary and alternative medicine (CAM). Rates of CAM use have increased since 2002, with mind-body therapies (MBT) composing 75% of this rise. Evidence to support the therapeutic use of MBT (including yoga, tai chi, qi gong, meditation, guided imagery, progressive muscle relaxation, and deep-breathing exercises) is growing. Little is known about the use of ...

BACKGROUND Muscle-biased therapies (MBT) are commonly used to treat pain, yet several reviews suggest evidence for the clinical effectiveness of these therapies is lacking. Inadequate treatment parameters have been suggested to account for inconsistent effects across studies. Pain sensitivity may serve as an intermediate physiologic endpoint helping to establish optimal MBT treatment parameters...

OBJECTIVES Few studies outside United Kingdom have documented effects of mentalization-based treatment (MBT) for patients with borderline personality disorder (BPD). This study aimed to investigate outcomes for BPD patients treated in an MBT programme in a Norwegian specialist treatment unit and compare benefits of the implemented MBT with the unit's former psychodynamic treatment programme. ...

BACKGROUND In Drosophila embryos, the midblastula transition (MBT) dramatically remodels the cell cycle during the 14(th) interphase. Before the MBT, each cycle is composed of only a short S phase and mitosis. At the MBT, S phase is dramatically lengthened by the onset of late replication, and a G2 phase is introduced. Both changes set the stage for gastrulation and require downregulation of Cd...

Model-based testing (MBT) relies on models of a system under test and/or its environment to derive test cases for the system. This paper discusses the process of MBT and defines a taxonomy that covers the key aspects of MBT approaches. It is intended to help with understanding the characteristics, similarities and differences of those approaches, and with classifying the approach used in a part...