objective(s) aristolochia indica has been widely used in the traditional medicine for the treatment of a variety of diseases. in the present study different extracts of roots of a. indica were evaluated for their anti­inflammatory, antipruritic and mast cell stabilizing activity. materials and methods anti-inflammatory activity was performed by compound 48/80 induced rat paw edema model and ant...

Objective(s) Aristolochia indica has been widely used in the traditional medicine for the treatment of a variety of diseases. In the present study different extracts of roots of A. indica were evaluated for their anti‌inflammatory, antipruritic and mast cell stabilizing activity. Materials and Methods Anti-inflammatory activity was performed by compound 48/80 induced rat paw edema model and ...

OBJECTIVES Aristolochia indica has been widely used in the traditional medicine for the treatment of a variety of diseases. In the present study different extracts of roots of A. indica were evaluated for their anti-inflammatory, antipruritic and mast cell stabilizing activity. MATERIALS AND METHODS Anti-inflammatory activity was performed by compound 48/80 induced rat paw edema model and ant...

The mast cell has long been associated with asthma, since it releases a variety of preformed and newly synthesized mediators that account for several features of asthma. Among the mediators, histamine is a wellcharacterized and the most potent vasoactive mediator in acute bronchoconstriction. In the present study, albino rats were sensitised by horse serum along with triple antigen containing B...

The objectives of this study were to investigate the temporal response of left ventricular (LV) matrix metalloproteinase (MMP) activity and collagen volume fraction (CVF) induced by an aortocaval fistula and the role of cardiac mast cells in regulating MMP activity. LV tissue was analyzed for MMP activity, CVF, and mast cell number in rats euthanized at 0.5, 1, 2, 3, 5, 14, 21, 35, and 56 days....

Mast cells play a vital role in the defence of the human body. Mast cell degranulation has been implicated in various ailments including allergies, bronchial asthma, interstitial cystitis, breast cancer, urticaria, etc. Hence mast cell stabilizers play a significant role in the prevention of these disorders. The primary objective of this review is to study the reports on different plants contai...

The influence of the ethanolic extract of roots of Inula racemosa linn on degranulation of rat peritoneal mast cell induced by compound 48/80 and Egg albumin was studied. The inhibitory effect of the extract was significant in immunologically induced degranulation of mast cells.

There is a high prevalence of usage of complementary and alternative medicines for the treatment of bronchial asthma which is considered as a chronic inflammatory disorder of the airways. Abutilon indicum G. Don. (Fam: Malvaceae) is abundantly found as a weed throughout the tropical parts of India. It is reported to have anti-inflammatory action and is used internally for inflammation of the bl...