the aim of this study was to determine the effect of marker density, level of heritability, number of qtls, and size of training set on the genomic accuracy over three generations. thereby, a trait was simulated with heritability of 0.10, 0.25 or 0.40. for each animal, a genome with 20 chromosomes, 1 morgan each, was simulated. different marker densities (2000, 4000 and 6000 markers) and 400 an...

The aim of this study was to determine the effect of marker density, level of heritability, number of QTLs, and size of training set on the genomic accuracy over three generations. Thereby, a trait was simulated with heritability of 0.10, 0.25 or 0.40. For each animal, a genome with 20 chromosomes, 1 Morgan each, was simulated. Different marker densities (2000, 4000 and 6000 markers) and 400 an...

genomic selection is a method to predict the breeding values of individuals using a large number of single nucleotide polymorphism markers. the cost of the high-density marker panel genotyping is very high, which prevents the widely application of genomic selection. the present simulation study was carried out to evaluate the use of low to medium marker density panels to predict direct genomic ...

The success of genomic selection mainly depends on the extent of linkage disequilibrium (LD) between markers and quantitative trait loci (QTL), number of QTL and heritability (h2) of the traits. The extent of LD depends on the genetic structure of the population and marker density. This study was conducted to determine the effects of marker density, level of heritability, number of QTL, and to ...

the objective of this study was to evaluate the potential gain in accuracy of predictions by imputing genotypes from a low-density marker panel (6640 marker with 10 replicates) to a medium-density marker panel in a simulated population of jersey cattle using fimpute software and also to evaluate the reliability of genomic estimate of breeding values (gebv) for milk yield (h2=0.40) and fertility...

background : angiogenesis is essential for the growth, invasion and metastasis of solid tumors. research on related factors such as microvessel density can be helpful in predicting a tumor's behavior. cd105 has been introduced as a marker of angiogenesis which stains vessels that are in the proliferating stage. there are some controversies about the relation of microvessel density and clinicopa...