history and objectives: considering the incremental trend for using the stimulatory drugs for ovulation and the new techniques for the treatment of infertility, therefore there is a higher incidence for the syndrome of polycystic ovaries. in this research study mannitol serum was used as a preventive agent in patients with such a syndrome referred to sarem medical center from 1999 to 2000. mate...

The effect of mannitol on serum and urine electrolytes and osmolality was investigated intraoperatively in neurosurgical patients. Patients in Group A (n = 7) received 1 gm . kg-1 of 20 per cent mannitol ("low"-dose) and in Group B, (n = 7) 2 gm . kg-1 ("high"-dose). There was a significant decrease in serum sodium and bicarbonate, and a significant increase in serum osmolality in both groups a...

BACKGROUND Mannitol and hypertonic saline are used to ameliorate brain edema and intracranial hypertension during and after craniotomy. We hypothesized that the agreement of measured and calculated serum osmolality during the infusion of hypertonic saline would be better than mannitol. The objective was to determine the accuracy of serum osmolality estimation by different formulas during the ad...

Stroke is the leading cause of mortality world wide. The most common complications of mannitol therapy are fluid and electrolyte imbalances. In the present study 25 patients of stroke and 25 healthy individuals were taken as controls. Serum sodium and Serum potassium were estimated by flame photometer. Hyponatremia was seen on first day of admission before giving mannitol as compared to control...

OBJECTIVE The aim of this study to investigate the normal values of erythropoietin (EPO) and neuroprotective effects of quercetin and mannitol on EPO and hematocrit levels after acute severe traumatic brain injury (TBI) in rat model. METHODS A weight-drop impact acceleration model of TBI was used on 40 male Wistar rats. The animals were divided into sham (group I), TBI (group II), TBI+quercet...

1. A comparison has been made between alkaline mannitol diuresis and alkaline glucose diuresis in the treatment of salicylate poisoning during an 8 hr period. 2. Mannitol gave a higher rate of urine flow, but there was no significant difference in the rate of salicylate excretion. 3. Serum levels of sodium, potassium and calcium fell in both groups, mainly during the first 2 hr. The mean fall i...

Increased intracranial pressure is a further effect of brain injury due to structural damage and osmotic water imbalances (Edema). Mannitol works in the proximal tubules mannitol absorption tubular cells by mechanism pinocytosis. The fluid transfer will draw into intracellular, so that cell be switched broke. This phenomenon referred as "Nephrosis Osmotic", which administration may occur result...

OBJECTIVE To compare the efficacy and side effects of hypertronic saline and mannitol use in cerebral edema. DESIGN Retrospective study. SETTING Pediatric intensive care unit. SUBJECTS 67 patients with cerebral edema. METHODS Patients with cerebral edema treated with either mannitol or hypertronic saline (HS) (Group II: n = 25), and both mannitol and HS (Group III: n = 20) were evaluate...