INTRODUCTION To compare the lip closing force of patients with mandibular prognathism to that of patients without dentofacial anomalies. METHODS The subject group included 62 female patients of Class III relationship with mandibular prognathism. The control group been comprised of 71 patients of Class I relationships without skeletal deformities. Maximum lip closing force and average lip clos...

BACKGROUND It is well known that genetic components play an important role in the etiology of mandibular prognathism, but few susceptibility loci have been mapped. METHODOLOGY In order to identify linkage regions for mandibular prognathism, we analyzed two Chinese pedigrees with 6,090 genome-wide single-nucleotide polymorphism (SNP) markers from Illumina Linkage-12 DNA Analysis Kit (average s...

BACKGROUND Failure to maintain a patent airway can result in brain damage or death. In patients with mandibular prognathism or retrognathism, intubation is generally thought to be difficult. We determined the degree of difficulty of airway management in patients with mandibular deformity using anatomic criteria to define and grade difficulty of endotracheal intubation with direct laryngoscopy. ...

INTRODUCTION Several candidate loci have been suggested as influencing mandibular prognathism (1p22.1, 1p22.2, 1p36, 3q26.2, 5p13-p12, 6q25, 11q22.2-q22.3, 12q23, 12q13.13, and 19p13.2). The goal of this study was to replicate these results in a well-characterized homogeneous sample set. METHODS Thirty-three single nucleotide polymorphisms spanning all candidate regions were studied in 44 pro...

The form and size of the human mandible is subject to considerable variation from the accepted normal. One of the more interesting and rewarding aspects of oral surgery is the operative correction of the Mandibular abnormalities, the category of malformation into which the mandibular deformity falls. In this study we reviewed more than 30 articles to clarify the mandibular prognathism with its ...

BACKGROUND/AIM The middle part of the face, that is the maxilla, has always been mentioned as a possible etiologic factor of skeletal Class III. However, the importance of the relationship of maxillary retroposition towards the cranial base is still unclear, although it has been examined many times. The aim of this study was to conduct cephalometric analysis of the morphology of maxilla, includ...

Background/Aim. Mandibular prognathism, as one of the more severe forms dentofacial deformities, impairs oral functions and appearance patient?s face represents a psychosocial handicap with negative impact on quality life (QoL). The aim study was to assess orthodontic-surgical (OS) treatment QoL patients mandibular prognathism. Methods. involved 40 (19 men 21 women, mean age 24.1 ? 4.1 years) w...

PURPOSE The purpose of this study was to compare asymmetric mandibular prognathism individuals with symmetric mandibular prognathism individuals using a new alternate spherical coordinate system. MATERIALS AND METHODS This study consisted of 47 computed tomographic images of patients with mandibular prognathism. The patients were classified into symmetric and asymmetric groups. Mandibular and...

Causation of a disease and a symptom generally is classified as genetic inheritance and environmental factors. A disease caused by a single gene disorder is defined as a disease that is attributed to a monogenic factor. A single gene disorder has been reported in more than 3,000 hereditary diseases. On the other hand, a polygenic or multifactorial disease is attributed to some susceptibility ge...

background : acromegaly, a condition which is associated with an acquired progressive disfigurement mainly involving the face and extremities, is a clinical syndrome which results from excessive production of growth hormone (gh) most commonly due to adenoma of the pituitary gland. acromegaly is a rare disease which due to its slow progression, is mostly diagnosed in late adulthood. bilateral sy...