Everybody is born with the mammary gland. Mammary gland development occurs through various stages throughout embryonic, and stays dormant for males. Although it uncommon, male also gets breast cancer, occasionally. Male cancer accounts approximately 1% of all cases, increasing. When compared other rare diseases, understudied. Typically, treated in same way as female cancer. In this article, asp...

Lactation is under homeostatic control, and sustained milk stasis or weaning leads to mammary gland involution. This transition is under the control of systemic and local factors. Of all the phases of mammary gland development, involution is the least well understood. Recent epidemiological observations suggest that involution events promote breast diseases, including breast cancer. This has re...

The stromal microenvironment regulates mammary gland branching morphogenesis. We have observed that mast cells are present in the mammary gland throughout its postnatal development and, in particular, are found around the terminal end buds and ductal epithelium of the pubertal gland. Mast cells contribute to allergy, inflammatory diseases, and cancer development but have not been implicated in ...

Angiotensin II (AngII) is a vasopressor hormone that has critical roles in maintenance of normal blood pressure and pathogenesis of cardiovascular diseases. We previously generated pregnancy-associated hypertensive (PAH) mice by mating female human angiotensinogen transgenic mice with male human renin transgenic mice. PAH mice exhibit hypertension in late pregnancy by overproducing AngII. A rec...

objectives: in traditional medicine salvia officinalis (sage) has been used as menstrual cycle regulator. in the present study the effects of sage extract on breast tissue were examined. materials and methods: fourteen female rats were divided into two groups: 1) distilled water-treated rats (con) that were gavaged with 1ml distilled water and 2) saliva officinalis hydroalcoholic extract (she)-...

a fibroadenoma was diagnosed in the mammary gland of a lamb by immunohistochemical method andmeasurement of oestradiol hormone. the tumor was characterized by an encapsulated firm mass with acreamy-white cut surface. histologically, it consisted of variably-sized sinus ducts, covered by a single ormultiple layers of proliferated epithelial cells, and embedded in a loose connective tissue. immun...

Objectives: In traditional medicine Salvia officinalis (sage) has been used as menstrual cycle regulator. In the present study the effects of sage extract on breast tissue were examined. Materials and Methods: Fourteen female rats were divided into two groups: 1) Distilled water-treated rats (Con) that were gavaged with 1ml distilled water and 2) Saliva officinalis hydroalcoholic extract (SHE)-...