نتایج جستجو برای: malarial antibodies
تعداد نتایج: 164892 فیلتر نتایج به سال:
the ifa and the blue dye decolourization g6pd tests were applied in three cross-sectional studies to find out were applied in three cross-sectional studies to find out the relationship of malarial antibodies and g6pd deficiency in the male residents of the malarious areas of southern iran. in the first study that the blood samples were collected in a random sampling method from the whole hormoz...
When rhesus monkeys with acute Plasmodium knowlesi infection recover after administration of quinine, complement-fixing antibodies are present at maximum titer in the serum soon after the first acute infection has subsided (1), and protective (2) and agglutinating (3) antibodies are demonstrable somewhat later in the course of the chronic disease. Relapses cause an increase in the titer of comp...
Antibodies play major roles in immunity to malaria; however, a limited understanding of mechanisms mediating protection is a major barrier to vaccine development. We have demonstrated that acquired human anti-malarial antibodies promote complement deposition on the merozoite to mediate inhibition of erythrocyte invasion through C1q fixation and activation of the classical complement pathway. An...
During pregnancy immunoglobulin G (IgG) antibodies are transferred from mother to neonate across the placenta. Studies in high transmission areas have shown transfer of P. falciparum-specific IgG, but the extent and factors influencing maternal-foetal transfer in low transmission areas co-endemic for both P. falciparum and P. vivax are unknown. Pregnant women were screened weekly for Plasmodium...
A total of 618 sera from inhabitants living in various endemic areas in Indonesia were examined for IgG against Plasmodium falciparum utilizing young trophozoites and mature schizonts as antigens by the method of ELISA and IFAT. In general, antibodies against trophozites (RESA) based on ELISA and antibodies against schizonts based on IFAT showed a correlation of malarial antibodies with the lev...
Repeated inoculation of mice, monkeys, and humans with x-irradiated sporozoites can lead to sterile immunity against malarial infection (1, 2), Vaccinated animals have serum antibodies capable of neutralizing sporozoites (3) and of reacting with their surface membranes (4, 5). Exposure of humans to infected mosquitoes in endemic areas leads to the development of relatively high serum titers o f...
The extreme presentation of hyperreactive malaria is hyperreactive malarial splenomegaly syndrome (HMS). Some patients present with a less pronounced syndrome. To investigate whether the degree of splenomegaly correlates with the degree of immune stimulation, whether prophylaxis or recent treatment play a role, and whether short therapy alone is effective, we examined retrospectively the medica...
The effect of well-characterized monoclonal antibodies to red cell surface molecules on the invasion of human red cells by the malarial parasites Plasmodium falciparum and Plasmodium knowlesi was examined. Antibodies to glycophorin A (GP alpha) inhibit invasion for both parasite species, and this is highly correlated with the degree to which they decrease red cell membrane deformability as meas...
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