objective : the study evaluated the efficacy and safety of vaginal rogesterone on prevention of recurrent preterm labor. materials and methods: total number of 70 patients with preterm labor treated with intravenous magnesium sulfate in perinatology department of valiasr hospital entered to a randomized clinical trial. treatment group after inhibition of preterm labor with magnesium sulfate rec...

Preterm delivery is a public health issue of major proportion. More than 12% of deliveries in the United States that occur at less than 37 weeks gestation preterm labor (PTL) represents the largest single reason for preterm birth (PTB). Attempts to prevent PTB have been unsuccessful. This paper of maintenance tocolytic therapy will examine the efficacy and safety of the drugs, both oral and sub...

Tocolysis means drug-induced Inhibition of premature or excessive uterine activity [38], Other terms, such äs "sedation of the irritated myometrium" or "relaxation of the uterus" have the same meaning; they are, however, not commonly applied [10, 11, 17, 29]. At the beginning of the research for new substances with inhibitory effect on the uterus it was postulated that progesterone or newlydeve...

A dichorionic diamniotic twin pregnancy was obtained by in vitro fertilization, in a 31 year old primigravida, with a history of endometriosis and antiphospholipid syndrome, revealed by several thrombo-embolic events on treatment by low-molecularweight heparin. The pregnancy was complicated by threatened preterm labor at 29 and 32 weeks’ gestation and was hospitalised for tocolytic (atosiban) a...

BACKGROUND Magnesium sulphate has been used in some settings as a tocolytic agent to inhibit uterine activity in women in preterm labour with the aim of preventing preterm birth. OBJECTIVES To assess the effects of magnesium sulphate therapy given to women in threatened preterm labour with the aim of preventing preterm birth and its sequelae. SEARCH METHODS We searched the Cochrane Pregnanc...

AIM To investigate whether maternal intravenous beta-mimetic tocolytic therapy increases the risk of autistic spectrum disorders (ASD) and poorer behavioural and developmental outcomes. METHOD Our study is a prospective case-control study among 90 children between 1.5 and three years old. Cases (n = 46) were toddlers with betamimetic tocolytic exposure; control group toddlers (n = 44) were to...

Objectives: To assess and compare the maintenance of tocolysis in preterm labor by using vaginal intramuscular progesterone. Study design: Randomized controlled trial. Settings study duration: Department Obstetrics & Gynecology, Civil Hospital, Bahawalpur between 12th March 2019 11th September Materials Methods: A total 96 women ranging from 18 40 years age presented with threatened labour,...