نتایج جستجو برای: mad

تعداد نتایج: 3764  

Journal: :SFU Educational Review 2019

MaD

Journal: :Interactions 2015

ناحیه هنزا در بخش جنوبی کمربند فلززایی ارومیه- دختر واقع در جنوب شرقی ایران است. این ناحیه شامل چندین کانسار مس پورفیری بوده و برای اکتشاف این نوع کانی‌سازی محیط مطلوبی است. برای مطالعات ژئوشیمیایی اکتشافی تعداد 451 نمونه رسوبات آبراهه‌ای از این ناحیه برداشت شده است. هدف شناسایی مناطق کانی‌زایی و استفاده از روشی مطلوب جهت تعیین حد آستانه عناصر است. در این پژوهش حد آستانه عناصر توسط دو روش تحلیل...

Journal: :Cell 1995
Donald E Ayer Quentin A Lawrence Robert N Eisenman

The bHLH-ZIP protein Mad heterodimerizes with Max as a sequence-specific transcriptional repressor. Mad is rapidly induced upon differentiation, and the associated switch from Myc-Max to Mad-Max heterocomplexes seem to repress genes normally activated by Myc-Max. We have identified two related mammalian cDNAs that encode Mad-binding proteins. Both possess sequence homology with the yeast transc...

Journal: :The Journal of Cell Biology 1995
I Västrik A Kaipainen T L Penttilä A Lymboussakis R Alitalo M Parvinen K Alitalo

Mad is a basic region helix-loop-helix leucine zipper transcription factor which can dimerize with the Max protein and antagonize transcriptional activation by the Myc-Max transcription factor heterodimer. While the expression of Myc is necessary for cell proliferation, the expression of Mad is induced upon differentiation of at least some leukemia cell lines. Here, the expression of the mad ge...

Journal: :Seizure 2012
Stéphane Auvin

The modified Atkins diet (MAD) consists of a nearly balanced diet without any age-dependent restriction of recommended daily calorie intake. Recently, there has been a marked increase in the use of the MAD in the treatment of epilepsy. Over the last 8 years, evidence suggesting that the MAD may exhibit similar anticonvulsant properties as the traditional ketogenic diet (KD) has been accumulatin...

2014
Ben Short

M oyle et al. de-s c r i b e h ow the C. elegans BUB-1 kinase helps recruit the spindle checkpoint proteins MAD-1 and MAD-2 to unattached kinetochores. During mitosis, the MAD-1–MAD-2 complex binds to kinetochores that haven't attached to the spindle and generates a signal that prevents cells from entering anaphase until the correct attachments are formed. Several kinetochore proteins are requi...

2006
Bart Kastermans BART KASTERMANS

The notion of very mad family is a strengthening of the notion of mad family of functions. Here we show existence of very mad families in different contexts.

Journal: :Genetics 1995
J J Sekelsky S J Newfeld L A Raftery E H Chartoff W M Gelbart

The decapentaplegic (dpp) gene of Drosophila melanogaster encodes a growth factor that belongs to the transforming growth factor-beta (TGF-beta) superfamily and that plays a central role in multiple cell-cell signaling events throughout development. Through genetic screens we are seeking to identify other functions that act upstream, downstream or in concert with dpp to mediate its signaling ro...

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