amyloidosis cutis dyschromica (acd) is a rare form of macular amyloidosis characterized by hypo and hyperpigmented macules. here we described a 20 year old girl with diffuse hypo and hyperpigmentation since she was four years old. five other members of her family are also involved. biopsy of hyperpigmented lesions revealed increase of melanin in the basal layer, pigment incontinence and amorpho...

Macular amyloidosis is a major cause of skin pigmentation and a rare form of localized primary cutaneous amyloidosis in western countries, with a higher prevalence in Asia and South America. The etiopathogenesis of macular amyloidosis has not yet been fully clarified; a number of risk factors are involved, among them chronic friction in particular. A 54-year-old patient with macular amyloidosis...

the study was undertaken to answer the question that how many patients with pigmentation of back and arms actually have amyloid deposits in pathology. 44 patients presenting with diffuse pigmentation of back and arms (dpoba) were selected. skin biopsies were performed in all cases from the affected sites. on all formalin fixed and paraffin embedded specimens, the following histochemical stains ...

Primary localized cutaneous amyloidosis (PLCA) is caused by the extracellular deposition of amyloid material in the skin without other cutaneous or systemic organ involvement. PCLA is classified into lichen, macular,and nodular amyloidosis. Macular amyloidosis and lichen amyloidosis are named as biphasic amyloidosis when they are concurrently seen in a patient. The treatment of this disease is ...

Macular amyloidosis is a form of cutaneous amyloidosis characterized by dusky-brown lesions usually located on the upper back between the shoulder blades. This report describes the case of a 45 year-old female presenting with hyperpigmented macules and lace-like, non-pruritic erythema in the sacral and cervical region as well as on both arms and legs. Histology revealed amyloid deposits in the ...

Amyloid is a proteinaceous material that is deposited in the tissues in a large variety of clinical contexts; in the skin it can be found with or without concomitant systemic disease. Primary localized cutaneous amyloidosis encompasses those amyloidoses restricted to the skin without involvement of other systems. The most common forms within this group are macular and lichen amyloidosis. Nodula...

National Skin Centre, 1 Mandalay Road, Singapore 308205 Primary cutaneous amyloidosis is a chronic pruritic disorder with characteristic amyloid deposits in the papillary dermis. The manifestations of primary localised cutaneous amyloidosis (PLCA) are usually confined to the skin. The aetiopathogenesis of PLCA has not been clearly elucidated. We report a patient who developed PLCA after a short...

Macular amyloidosis (MA) is the subtlest of cutaneous varieties amyloidosis. In general, treatment MA disappointing. Hence, this study was aimed at comparing two modalities for same. To compare efficacy 30% TCA chemical peel with Q switched Nd-YAG laser 1064nm in macular 50 patients attending our Dermatology outpatient department were enrolled study. The involved application 25 an interval 2 we...