Point spread function (PSF) plays an essential role in image reconstruction. In the context of confocal microscopy, optical performance degrades towards the edge of the field of view as astigmatism, coma and vignetting. Thus, one should expect the related artifacts to be even stronger in macroscopy, where the field of view is much larger. The field aberrations in macroscopy fluorescence imaging...

Cholesterol-core nanoparticles (LDE) have been shown to be recognized by low-density lipoprotein receptors (LDLR) after administration; therefore, LDE is an ideal vehicle to deliver drug with targeting property. Paclitaxel, when incorporated into LDE, promotes atherosclerosis regression with reduced drug toxicity in rabbits through LDLR. Here, we tested whether LDE-paclitaxel could still be eff...

Various pharmacognostic parameters including macroscopy, microscopy, chemomicroscopy and behaviour of powdered drug on treatment with different chemical reagents were studied on the leaves of Bauhinia purpurea Linn. (Family Caesalpinaceae). Phytochemical screening of the plant part with various solvents revealed the presence of phenolic compounds, tannins, flavonoids, phytosterols, saponins and...

The J. curcas is considered as a biofuel plant, but the leaves are traditionally used as an antiinflammatory and anticoagulant. In present investigation, the detailed pharmacognostic study of J. curcas leaf is carried out to lay down the standards which could be useful in future experimental studies. The study includes macroscopy, microscopy, preliminary phytochemical screening and physicochemi...

The leaf of Lagenaria siceraria is considered as a hypolipidemic in folklore medicine. In present investigation, the detailed pharmacognostic study of Lagenaria siceraria leaf is carried out to lay down the standards which could be useful in future experimental studies. The study includes macroscopy, microscopy, preliminary phytochemical screening and physicochemical evaluation.

Several authors have reported schistosomiasis caused by Schistosoma haematobium in the female genital tract of patients in endemic areas. This work describes tubal schistosomiasis by Schistosoma mansoni in a Brazilian woman submitted to hysterectomy for uterine myomatosis and metrorrhagia. Macroscopy evidenced hydrosalpinx of the left tube and multiple Schistosoma mansoni eggs were identified b...

In this work, we have considered a new multimodality imaging for macroscopy based on Second Harmonic Generation (SHG) method to monitor invasivelessly the matrix collagen. As the triple helicoidally structure of collagen molecules appearing as not centrosymetric, very organized and spatially oriented, collagen fibrils give rise to a very strong SHG signal and can be imaged without any exogenous...