Extrapulmonary deposition of macroaggregated albumin particles on lung perfusion scintigraphy occurs in the presence of right-to-left shunting, as demonstrated in this case of portosystemic shunting related to superior vena cava obstruction by germ cell tumor of the mediastinum. The case demonstrates the importance of examining tracer deposition within the entire field of view on (99m)Tc-macroa...

A young woman with pulmonary hypertension due to sclerodermatous pulmonary vascular disease died immediately following the injection of macroaggregated albumin labeled with 99-TC for a perfusion lung scan. Review of the literature suggests that patients with chronic pulmonary hypertension due to an obliterative pulmonary vascular disease are at risk of developing a serious reaction to perfusion...

Lung scanning has been recognized as a clinically useful technique for portraying macroscopic pulmonary perfusion defects since it was first reported by Wagner in 1964 (1 ). A number of radiopharmaceuticals have been proposed to assess pulmonary perfusion. Although 1 3 1 I imposes many limitations as a radiotagging agent, the use of iodinated macroaggregated albumin (I-MAA) has received wide ac...

Herein, the synthesis of macroaggregated albumin particles was carried out under different conditions for size optimization that can be used in Magnetic resonance and fluorescence imaging. The distribution analysis performed with Mastersizer optimized MAA had 31.57 µm 0.36 PDI value. Morphological done SEM. EDX FT-IR analyzes were by forming Eu3+ Tb3+ complexes MAA. lungs liver imaging have bee...