it has recently been shown that ror1, a member of the receptor tyrosine kinase family, is overexpressed in leukemic b cells of chronic lymphocytic leukemia (cll) and a subset of acute lymphoblastic leukemia (all). in this comparative study the expression profile of ror1 mrna was investigated in iranian patients with cll and acute myelogenous leukemia (aml) and the results were compared with tho...

abstract objective fever and neutropenia are a common complication of chemotherapy in cancer. it is usually managed by hospitalization and empiric administration of antibiotics. use of fluroquinolones is limited because of joint/cartilage toxicity. this study attempted to compare the efficacy of oral ciprofloxacin with intravenous ceftazidim in low risk febrile neutropenic lymphocytic leukemia....

1. dept. of hematology and medical oncology, kermanshah university of medical sciences, kermanshah, iran 2. students research committee, kermanshah university of medical sciences, kermanshah, iran 3. medical biology research center, kermanshah university of medical sciences, kermanshah, iran                                     corresponding author: masoud sadeghi, msc. tel: (+98) 9185960644 ema...

abstract objective the great majority of patients with childhood leukemia become long-term survivors. they treated with chemotherapy and prophylactic central nervous system (cns) irradiation. the aim of this cross-sectional study was to evaluate effect of the long-term toxicity in all survivors, and possible effects of this treatment on their intellectual in compare with their sibling. material...

introduction campylobacter jejuni is a slender, motile, non-spore-forming, helical-shaped, gram-negative bacterium. it is one of the most common causes of human gastroenteritis in the world. the aim of this study was to present a patient with acute lymphocytic leukemia (all), who was infected with campylobacter jejuni. conclusions c. jejuni should be considered in the differential diagnosis as ...

Genome-editing systems such as Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 technology have uncovered new opportunities to model diseases chronic lymphocytic leukemia. CRISPR/Cas9 is an important means of advancing functional studies Chronic Lymphocytic Leukemia (CLL) through the incorporation, elimination and modification somatic mutations in CLL models.

background: the present study was aimed to examine the possible association between methylene tetrahydrofolate reductase (mthfr) gene polymorphisms and childhood acute lymphoblastic leukemia (all) in a sample of iranian population. subjects and methods: a total of 220 subjects including 100 children diagnosed with all and 120 healthy children participated in the case-control study. the single n...

fuzzy expert systems are one of the most practical intelligent models with the high potential for managing uncertainty associated to the medical diagnosis. in this paper, a fuzzy inference system (fis) for diagnosing of acute lymphocytic leukemia in children has been introduced. the fuzzy expert system applies mamdani reasoning model that has high interpretability to explain system results to e...

chronic lymphocytic leukemia (cll) and chronic myeloid leukemia (cml) are the most common leukemias of the elderly (>43 year). however, the sequential occurrence of cml followed by cll in the same patient is extremely rare. in our report, a 52-year-old female was diagnosed with cll (type of bone marrow (bm) infiltration was nodular and interstitial) and was treated with chlorambucil. 64 months ...