background: worldwide, cervical cancer is one of the most challenging gynecologic cancers in treatment. objectives: this study was designed with the aim of comparing patients treated with external beam radiotherapy (ebrt) and interactivity brachytherapy (icbt) with ebrt and extrafascial hysterectomy in locally advanced stages of cervical cancer (iib-iii). patients and methods: the present study...

Lymphangioma is a rare benign disease of the lymphatic vessels. Typically, they are primary conditions but may be acquired secondarily, such as those caused by irradiation during radiotherapy for the treatment of breast cancer. The local lymphatic obstruction provoked by irradiation causes the appearance of asymptomatic hyaline vesicles on the irradiated skin. The present report describes a 78-...

Systemic delivery of an anti-cancer agent often leads to only a small fraction of the administered dose accumulating in target sites. Delivering anti-cancer agents through the lymphatic network can achieve more efficient drug delivery for the treatment of lymph node metastasis. We show for the first time that polymeric gold nanorods (PAuNRs) can be delivered efficiently from an accessory axilla...

Because of the deficiency lymphatic reflux in tumor, retention tumor interstitial fluid causes aggravation pressure (TIP), which leads to unsatisfactory penetration nanomedicine. It is main inducement recurrence and metastasis. Herein, we design a pyroelectric catalysis-based Nano-lymphatic decrease TIP for enhanced treatments. realizes photothermal therapy decomposition under NIR-II laser irra...

Growth hormone (GH) secretion was studied in 15 children at various times after treatment for acute lymphatic leukaemia. Impaired GH responses both to hypoglycaemia and to Bovril were found in 4 children. 13 of the children had been given prophylactic cranial irradiation of either 2500 rads in 10 fractions or 2400 rads in 20 fractions. The reduction in GH responses in those given the former dos...

1. Weights and ,-glucuronidase activity have been determined in lymphatic organs ofrats (lymph nodes of the neck, thymus and spleen) from 4 hr. to 15 days after total-body irradiation (200, 400 and 600 r.). 2. The activity of the enzyme increased in the first period after the irradiation (from 4 hr. to 5 days) when the tissues underwent a rapid decrease in weight. Histological examination showe...

Lymphatic metastasis is common in advanced-stage carcinoma and is associated with a poor prognosis. However, few effective treatments to inhibit it are available. Z-100 is an immunomodulatory extract of Mycobacterium tuberculosis strain Aoyama B that contains polysaccharides such as arabinomannan and mannan. Here, we investigated the inhibitory effect of Z-100 on spontaneous lymphatic metastasi...

Bone marrow (BM)-derived circulating endothelial precursor cells (CEPCs) have been reported to incorporate into newly formed blood vessels under physiologic and pathologic conditions. However, it is unknown if CEPCs contribute to lymphangiogenesis. Here we show that in a corneal lymphangiogenesis model of irradiated mice reconstituted with enhanced green fluorescent protein (EGFP)-positive dono...

The thymus (T)-and bursa (BF)-dependent areas of the duck lymph node were histologically examined by means of chemical bursectomy using cyclophosphamide-treatment , surgical thymectomy, and/or X-ray irradiation. The T-dependent area was represented by the deep area of lymphatic nodules comprised of small lymphocytes. The BF-dependent one was represented by lymphatic cords consisting of small an...