Thirty-two patients with systemic lupus erythematosus were evaluated clinically and with computed tomography in order to determine whether the occurrence of cerebral atrophy in systemic lupus erythematosus was due to the steroid therapy or the cerebral manifestations of the disease itself. Of these patients, 14 had central nervous system manifestations of the disease (lupus cerebritis) and 12 o...

objective systemic lupus erythematosus (sle), an autoimmune systemic disease with unknown etiology, affects virtually every part of the body; involvement of the central nervous system (cns) is one of the major causes of morbidity and mortality in systemic lupus erythematosus (sle) patients and is the least understood aspect of the disease. neutropenia is very uncommon in childhood lupus. true n...

Objective Lupus cerebritis is a rare but potentially fatal complication of SLE. Prompt diagnosis and rapid initiation therapy can prove lifesaving. Background We present the case 31-year-old woman who presented to emergency department with one week fevers, headaches confusion. Review systems was notable for diffuse muscle joint pains, weakness rash. SLE Sjogren's were both diagnosed six months ...

Ptosis is only rarely mentioned as a manifestation of systemic lupus erythematosus (SLE) and is generally interpreted as an indication of cerebral disease (Harvey et al., 1954; Grigor et al., 1978; Feinglass et al., 1976). As we had observed ptosis in the absence of cerebral lupus, we reviewed the records of all SLE patients with ptosis seen in our unit over the past six years in order to ascer...

Systemic Lupus erythematosus (SLE) is an autoimmune disease with multiple clinical presentations and manifestations. Here, we report an intriguing case of a 30-year-old female with full-blown SLE, associated with longitudinal extensive transverse myelitis (LETM) on Magnetic Resonance Imaging (MRI) manifested by lower extremity weakness, neurogenic bladder and bowel, and central nervous system (...

A 53-year-old female was admitted to the intensive care unit for lupus cerebritis; she had a 15-year history of stable lupus. Over the prior 1 to 2 months, the patient visited a tanning salon and this triggered the exacerbation of lupus. Her initial symptoms were cutaneous in the form of an erythematous rash. Within 2 weeks she started to have headaches and was admitted for seizure and psychosi...

Background: Neuropsychiatric systemic lupus erythematosus (NPSLE) has a diverse and broad spectrum of severity prognosis, with some devastating manifestations. However, its diagnosis treatment remain unclear controversial. Case Report: A 19-year-old woman SLE presented fever, headache, quadriparesis, tremor. Brain magnetic resonance imaging (MRI) showed sulcal enhancement in the cortical sulcus...