background:  in this study a series of basic dosimetric properties of a low-density (ld) gel dosimeter are investigated. the dose response is studied regarding to linearity, sensitivity, dose-rate and energy dependence as well as lung tissue equivalence. materials and methods: the ld gel was made by mixing the polymer gel with expanded polystyrene spheres. energy dependence was studied at two d...

We present the complete construction methodology for an anatomically accurate mouse phantom made using materials which mimic the characteristics of tissue, lung, and bone for radiation dosimetry studies. Phantoms were constructed using 2 mm thick slices of tissue equivalent material which was precision machined to clear regions for insertion of lung and bone equivalent material where appropriat...

Monte Carlo simulations of lung equivalent materials often involve the density being artificially lowered rather than a true tissue (or plastic) and air composition simulated. This study used atomic analysis to test suitability this method. Atomic was also 3D printing PLA or ABS with simulate tissue. It found that there minimal difference when using an density, 0.8 % in Nitrogen largest observe...

PURPOSE The aim of this work is to evaluate the application of tissue-specific dose kernels instead of water dose kernels to improve the accuracy of patient-specific dosimetry by taking tissue heterogeneities into consideration. MATERIALS AND METHODS Tissue-specific dose point kernels (DPKs) and dose voxel kernels (DVKs) for yttrium-90 (90Y), lutetium-177 (177Lu), and phosphorus-32 (32P) are ...

background: regular aerobic exercise improves the background: regular aerobic exercise improves the inflammatory status in different lung diseases. however, the effects of long-term aerobic exercise on the lung response have not been investigated. the present study evaluated the effect of aerobic exercise on the lung inflammatory. m aterials and methods: 12 adult male wistar rats were divided t...

introduction the potential hazards posed by exposure to radiation from radon have been of great concern worldwide, since it is especially associated with increased risk of lung cancer. some radioisotopes of radon progeny deposited in the human lungs emit β particles followed by the γ rays. while γ rays are comparatively less damaging to the respiratory system than α and β particles, it is the p...

For patients treated with lung stereotactic body radiation therapy (SBRT) using dynamic conformal arcs, the influence of inhomogeneity correction (IC) on normal tissue and tumor dosimetry was studied. For the same numbers of monitor units, the planning target volume equivalent uniform doses calculated without path-length IC were lower than those calculated with IC (mean difference 18%, range 1-...

Thoracic cancer treatment presents dosimetric difficulties due to respiratory motion and lung inhomogeneity. Monte Carlo and deformable image registration techniques have been proposed to be used in four-dimensional (4D) dose calculations to overcome the difficulties. This study validates the 4D Monte Carlo dosimetry with measurement, compares 4D dosimetry of different tumor sizes and tumor mot...

This article aims at presenting in a didactic way, dosimetry concepts and methods that are relevant for radio-embolization of the liver with 90 Y-microspheres. The application medical internal radiation dose formalism to is introduced. enables simplified dosimetry, where absorbed given tissue depends on only its mass initial activity. applied single-compartment method, partition model, liver, t...

Dose distributions in different models of inhomogeneous phantoms irradiated with 3 19 MeV electron beams have been calculated using DOSXYZnrc/EGSnrc Monte Carlo code. The rectilinear 3D voxel phantoms, relevant for radiotherapy and clinical dosimetry, were built from ICRU soft tissue equivalent material in which was inserted a single layer of bone, lung, air or Titanium. Significant interface e...