background and objectives: gliomas are the most prevalent primary brain tumors. the purpose of this retrospective cohort study was evaluation of clinical trend and prognosis of patients with brain glioma and effective factors in prognosis. materials and methods: hundred and forty-five patients with supratentorial brain glioma, treated in shahid mostafa khomeini & hazrat-e-rasool hospitals i...

Background & Objective Angiogenesis is an essential component of tumor growth. Expression of PSMA on the neo-vasculature of many solid tumors, including glioblastoma multi-form, has been determined. The pattern of expression suggests that PSMA may play a functional role in angiogenesis. Methods: expression of PSMA in dif...

  Background and Objectives: Gliomas are the most prevalent primary brain tumors. The purpose of this retrospective cohort study was evaluation of clinical trend and prognosis of patients with brain glioma and effective factors in prognosis. Materials and Methods: Hundred and forty-five patients with supratentorial brain glioma, treated in Shahid Mostafa Khomeini & Hazrat-e-...

Background& Objective: Micro-vascular proliferation is an important histological feature of brain glioma with more vascular proliferation is present in higher grades of glioma. CD 105 is expressed in new actively proliferating and immature endothelial cells in tumor environment  and appears to be capable to distinguish between malignant neo-vasculature and normal vesse...

balo's concentric multiple scleroses (ms) is a rare demyelinating disease and a variant of multiple sclerosis. we report a case with interesting misleading clinical history and typical ri findings of balo disease. a 19-year-old girl presented with fever and left hemiparesis following dental procedure 15 days ago. on physical examination fever and left limbs forces loss were noted. on ct scan a ...

Using cultured glioma cell line, we demonstrated in vitro and in vivo that when low grade glioma was pass through glioma cell culture at 19th passage, these tumor cells were malignantly transformed. This cell line was established from tissue culture of neurosurgical specimen, pathologically diagnosed as glioma (low grade glioma; grade 1-11) with glial fibrillary acidic protein (GFAP) positive b...